An observational study in Hepatitis, sponsored by The First Hospital of Jilin University. Completed at 1 site in China. Open to participants aged 20 Years to 85 Years. Per ClinicalTrials.gov, last updated 2020-10-20.
Sponsored by The First Hospital of Jilin University · Observational
The purpose of this study is to determine whether the morbidity of hepatitis C with Chinese population.
Hepatitis C virus (HCV) infection rate in China is about 3%, which means about 30 million patients. More importantly, many of those patients with chronic hepatitis C eventually develop cirrhosis and hepatocellular carcinoma(HCC).Our survey found the rate of hepatitis c infection in northeastern China without intervention is 34.3%, due to the abuse of caffeine sodium benzoate. This population has the similar mode of transmission, which is a fine study of the natural outcome hepatitis C. We plan to carry out epidemiological studies for this population, review of the influencing factors of the disease, and analyze the host factors that can effect the prognosis.
3,381 studies on the registry are indexed under Hepatitis; 202 are open to participants now.
This study's enrollment of 6,068 is above the median of 253 across 823 observational studies indexed under Hepatitis.
Browse Hepatitis studies →The First Hospital of Jilin University is the lead sponsor of 181 studies on the registry; 93 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients are from the northeast of China. Most of the patients have been infected by the hepatitis c virus due to the drug abuse. Many of them share the same syringe for drug intravenous injection. However, HIV infection has been rarely detected.
Exclusion Criteria:
Blood Anti-HCV
Co-infection status are analyzed.
Time frame: Baseline
Alanine Aminotransferase (ALT) and Aspartate transaminase (AST)
ALT AST are assayed to detect the hepatic function.
Time frame: Baseline
Fibrosis stage
Fibrosis is analyzed with Fibroscan.
Time frame: Baseline
Regular blood test
The distribution and absolute count of the different types of blood cells are assayed.
Time frame: Baseline
Blood HCV RNA Copies
Blood HCV RNA copies were assayed with Roche - COBAS® AmpliPrep/COBAS® TaqMan® HCV Test.
Time frame: Baseline
HCV genotype
HCV NS5A is cloned into T vector and sequenced for evolutionary analysis.
Time frame: Baseline
Drug abuse history
Patients will be asked about their drug usage history.
Time frame: Baseline
Alcohol ,smoking condition
Patients are asked whether they take alcohol or smoke cigarettes during the therapy period.
Time frame: Baseline
This study is completed, as verified in Oct 2020. You cannot join it, but the record below documents what was studied.
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The First Hospital of Jilin University