An observational study in Right Ventricular Dysfunction, sponsored by University of Minnesota. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-02-04.
Sponsored by University of Minnesota · Observational
This study will include the placement of a pressure volume (PV) loop catheter in the right atrium of patients undergoing left ventricular assist device (LVAD) placement and measure relevant PV loop data. Transesophageal echocardiography (TEE) and pulmonary artery (PA) catheter parameters as comparators to the PV loop will be recorded.
This will be a prospective observational study design to characterize right ventricular function in 5 consecutive patients undergoing LVAD implantation at the University of Minnesota Medical Center (UMMC). Pre-, intra- and postoperative care delivery to all enrolled and consented patients will meet the standards of care otherwise delivered to patients undergoing LVAD implantation at UMMC; care delivery will be at the discretion of the clinical care team and will not be altered based on the output of the right ventricular high-fidelity conductance catheters.
90 studies on the registry are indexed under Ventricular Dysfunction, Right; 28 are open to participants now.
This study's enrollment of 4 is below the median of 100 across 51 observational studies indexed under Ventricular Dysfunction, Right.
Browse Ventricular Dysfunction, Right studies →University of Minnesota is the lead sponsor of 1,216 studies on the registry; 197 are open to participants now.
Of its 136 completed or terminated interventional studies of FDA-regulated products, 95 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
All consecutive patients 18 years or older undergoing left ventricular assist device (LVAD) placement at the University of Minnesota Medical Center
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Characterize right ventricular function while undergoing LVAD implantation
Diagnostic Test: Hemodynamic assessment
Hemodynamic assessment of the right ventricle using pressure-volume loop catheter and pulmonary artery catheter
Stroke volume
Stroke volume will be reported in units of millilitres per square metre
Time frame: Approximately 4-6 hours
Heart rate
Heart rate will be reported in units of beats per minute
Time frame: Approximately 4-6 hours
Ejection fraction
Ejection fraction will be reported as a percent
Time frame: Approximately 4-6 hours
Cardiac output
Cardiac output will be reported in units of milliliters per minute
Time frame: Approximately 4-6 hours
End-systolic pressure
End-systolic pressure will be reported in units of mmHG
Time frame: Approximately 4-6 hours
End-systolic volume
End-systolic volume will be reported in units of milliliters
Time frame: Approximately 4-6 hours
End-diastolic pressure
End-diastolic pressure will be reported in units of mmHG
Time frame: Approximately 4-6 hours
End-diastolic volume
End-diastolic volume will be reported in units of milliliters
Time frame: Approximately 4-6 hours
Right ventricular dP/dt
Right ventricular dP/dt will be reported in units of mmHg per second
Time frame: Approximately 4-6 hours
Stroke work
Stroke work will be reported in units of gram meters (g\*m)
Time frame: Approximately 4-6 hours
Ran from Aug 2021 to primary completion in Dec 2024, 40 months.
Of 25 observational studies under Ventricular Dysfunction, Right, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 26. This study's 40 months is above that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.
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Ventricular Dysfunction, Right →