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CompletedNCT04448535Updated Oct 24, 2022

Effects of Ginkgo (Gingko Biloba) on Retinal and Choroidal Ocular Tissue

An interventional study of Gingko Biloba in Healthy, sponsored by State University of New York College of Optometry. Completed at 1 site in United States. Open to participants aged 20 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-10-24.

Sponsored by State University of New York College of Optometry · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
20 Years to 55 Years
Sex
All
01

Study summary

The purpose of this study is to understand the effect of Ginkgo Biloba oral supplements on retinal and choroidal ocular tissue.

Read the detailed description

The study objectives are to:

  1. assess the changes from pre- to post- oral supplementation on retinal and choroidal thickness and blood flow, retinal oxygen saturation, ocular perfusion pressure, and retinal function
02

Conditions studied

  • Healthy
03

In context

Lead sponsor

State University of New York College of Optometry is the lead sponsor of 17 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Aged between 20 - 55 years, inclusive
  • Good general and ocular health
  • Corrected visual acuity of 20/40 or better
  • No gingko biloba supplementation within the last 3 months

Exclusion criteria

Exclusion Criteria:

  • All significant ocular and any systemic disorders considered likely to affect the systemic or ocular vasculature
  • History of ocular surgery, including refractive surgery
  • Use of ocular medications
  • Conditions where ginkgo supplementation is contraindicated
  • Any eye or systemic disease that affect vision or refractive error
  • Current smokers
  • Subjects who are pregnant, breastfeeding, or planning conception
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Gingko Biloba

    oral intake of gingko biloba for 4 weeks

    Dietary Supplement: Gingko Biloba

Interventions

  • Dietary supplementGingko Biloba

    oral intake of Gingko Biloba, 240mg/day for 4 weeks

06

What researchers measure

Primary outcomes

  1. ocular blood flow

    ocular blood flow measured with doppler ultrasound

    Time frame: 4 weeks

07

Study locations

1 site
  • SUNY College of Optometry
    New York, New York 10036, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 24, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04448535
Lead sponsor
State University of New York College of Optometry
Responsible party
Alexandra Benavente (Associate Clinical Professor, State University of New York College of Optometry) — Principal investigator
First posted
Jun 26, 2020
Start date
Jan 1, 2021
Primary completion
Aug 3, 2022
Completion
Aug 3, 2022
Last update
Oct 24, 2022

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2022. You cannot join it, but the record below documents what was studied.

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