A Phase 2/3 interventional study of platlet rich plasma (PRP) and Triamcinolone Acetonide in Carpal Tunnel Syndrome, sponsored by Tanta University. Status unknown at 1 site in Egypt. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2020-06-16.
Sponsored by Tanta University · Phase 2/3, Interventional, and Treatment
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel. Group II received ultrasound guided injection of 2 mL steroids (40 mg triamcinolone acetonide). Group III received ultrasound guided injection of 2 mL saline as placebo control.
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel. Group II received ultrasound guided injection of 2 mL steroids (40 mg triamcinolone acetonide). Group III received ultrasound guided injection of 2 mL saline as placebo control.
Each group will be injected twice with 2 weeks intervals. All procedures were done after informed consent. Evaluation of the patients at baseline, 3 and 6 months after last injection was done clinically by measuring visual analogue scale (VAS), electrophysiologically (by measuring motor and sensory nerve conduction studies of median nerve using a standardized technique) and ultrasonographic study by measuring cross sectional area (CSA) of median nerve at the level of pisiform.
589 studies on the registry are indexed under Carpal Tunnel Syndrome; 139 are open to participants now.
This study's enrollment of 90 is above the median of 60 across 445 interventional studies indexed under Carpal Tunnel Syndrome.
Browse Carpal Tunnel Syndrome studies →Tanta University is the lead sponsor of 963 studies on the registry; 304 are open to participants now.
Of its 16 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
patients received ultrasound-guided injection of 2 mL PRP into the affected carpal tunnel.patients will be injected twice with 2 weeks intervals
Drug: platlet rich plasma (PRP)
patients received ultrasound-guided injection of 2 mL steroids (40 mg triamcinolone acetonide). into the affected carpal tunnel. patients will be injected twice with 2 weeks intervals
Drug: Triamcinolone Acetonide
patients received ultrasound-guided injection of 2 mL saline patients will be injected twice with 2 weeks intervals
Drug: Saline
Platelet-rich plasma (PRP) promotes angiogenesis, neurogenesis, and nerve regeneration, also it could reduce swelling and inflammation of the flexor tenosynovitis.
40 mg triamcinolone acetonide
Saline
visual analogue scale
Scale for assessement the degree of pain along 0-10 scale
Time frame: Change from 3 months after last injection and 6 months after last injection
measuring motor and sensory nerve conduction studies of median nerve using a standardized technique
electrophysiologically by measuring motor and sensory nerve conduction studies of median nerve using a standardized technique
Time frame: Change from 3 months after last injection and 6 months after last injection
cross-sectional area (CSA) of the median nerve at the level of the pisiform.
ultrasonographic study by measuring cross-sectional area (CSA) of the median nerve at the level of the pisiform.
Time frame: Change from 3 months after last injection and 6 months after last injection
Plan to share: Undecided
This study is status unknown, as verified in Jun 2020. You cannot join it, but the record below documents what was studied.
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Tanta University