CClinicalTrials.gg
Status unknownNCT04431505Updated Jul 16, 2020

Anaesthesia and Apoptosis

An observational study in Apoptosis, sponsored by Assiut University. Status unknown at 1 site in Egypt. Open to participants aged 1 Year to 10 Years. Per ClinicalTrials.gov, last updated 2020-07-16.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Jul 2020), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
20
Ages
1 Year to 10 Years
Sex
All
01

Study summary

Anesthetics cause widespread apoptosis in the developing brain, resulting in neurocognitive abnormalities. However, it is unknown whether anesthesia-induced neurotoxicity occurs in humans because there is currently no modality to assess for neuronal apoptosis in vivo

02

Conditions studied

  • Apoptosis
03

In context

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Year to 10 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

patients undergoing congenital heart corrective surgery

Inclusion criteria

  • congenital heart corrective surgery

Exclusion criteria

Exclusion Criteria:

  • none
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
20 participants (estimated)
Patient registry
No

Interventions

  • Otherapoptosis

    study of apoptotic changes due to anaesthesia

06

What researchers measure

Primary outcomes

  1. apoptotis during anaesthesia

    measuring markers of apoptosis pathway

    Time frame: 24 hours

07

Study locations

1 of 1 sites recruiting
  • Assiut university
    Assiut, 71111, Egypt
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 16, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04431505
Lead sponsor
Assiut University
Responsible party
Rasha Hamed (lecturer of anaesthesia, Assiut University) — Principal investigator
First posted
Jun 16, 2020
Start date
Jun 12, 2020
Primary completion
Dec 1, 2020 (estimated)
Completion
Dec 11, 2020 (estimated)
Last update
Jul 16, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2020. You cannot join it, but the record below documents what was studied.

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