An interventional study of thoracic epidural catheterization in Optic Nerve Sheath Diameter, sponsored by Keimyung University Dongsan Medical Center. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2020-11-18.
Sponsored by Keimyung University Dongsan Medical Center · Not applicable, Interventional, and Treatment
Valid method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. Different volume of injection is known to affect the degree of increase of intracranial pressure.
This study is desinged to measure the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.
Previous study showed that different volume of injections (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia showed siginifiant increase of optic nerve sheath diameter in group of high volumes. Increase of ICP can result in harmful effect including reduced cerebral flow and oxygen saturation. Also, increase of ICP can cause headache, syncope and transient loss of visual acuity. The proven and valid method of measuring ICP indirectly is using optic nerve sheath diameter.
This study was designed to examine the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.
Keimyung University Dongsan Medical Center is the lead sponsor of 81 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
low volume (5 cc) saline injection during thoracic epidural catheterization
Procedure: thoracic epidural catheterization
intermediate volume (10 cc) saline injection during thoracic epidural catheterization
Procedure: thoracic epidural catheterization
high volume (20 cc) saline injection during thoracic epidural catheterization
Procedure: thoracic epidural catheterization
thoracic epidural catheterization for postoperative pain control
optic nerve sheath change during 4 time period
optic nerve sheath change during 4 time period using ultrasound
Time frame: Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention
cerebral oxygenation change during 4 time period
cerebral oxygenation change during 4 time period using pressure monitoring kit
Time frame: Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention
Plan to share: No
This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.
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Keimyung University Dongsan Medical Center