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CompletedNCT04394988Updated May 20, 2020

Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections

An observational study in Incisional Hernia and Incision Infection, sponsored by Inonu University. Completed at 1 site in Turkey. Per ClinicalTrials.gov, last updated 2020-05-20.

Sponsored by Inonu University · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
102
Sex
All
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Study summary

In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate...) provides a remarkable advantage compared to open surgery, the need for the extraction site incision could not bring the incision-related morbidity rates to the desired level. That's why SILS and natural hole surgery came to the fore. Colorectal surgery was also affected by this process, and the laparoscopic colectomy procedure combined with transrectal colon extraction was first performed in 1993 (1). Although its use increased gradually after this period, it could not reach the expected levels and this could not resolve the concerns on natural hole surgery.

In this article, our aim is to present the single center results of the patients who performed the extraction with the NOSE method after laparoscopic colorectal surgery.

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Conditions studied

  • Incisional Hernia
  • Incision Infection

Keywords

  • natural orifice surgery
  • minimally invasive surgery
  • colon cancer
  • laparoscopic colorectal
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In context

Surgical Wound Infection

670 studies on the registry are indexed under Surgical Wound Infection; 141 are open to participants now.

This study's enrollment of 102 is below the median of 237 across 128 observational studies indexed under Surgical Wound Infection.

Browse Surgical Wound Infection studies →

Lead sponsor

Inonu University is the lead sponsor of 375 studies on the registry; 86 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients who underwent laparoscopic-natural orifice colectomy at General Surgery Clinic in Inonu University between January 2013 and July 2018

Inclusion criteria

  • patients who underwent laparoscopic - natural orifice colectomy.

Exclusion criteria

Exclusion Criteria:

  • patients with missing data
  • patients who underwent open colectomy
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
102 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. complications due to incision and aesthetic score

    Hernia, infection, hospital stay and aesthetic score

    Time frame: 6 months

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Study locations

1 site
  • Inonu University
    Malatya, Turkey
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References and documents

Publications

  • Gundogan E, Aktas A, Kayaalp C, Gonultas F, Sumer F. Two cases of laparoscopic total colectomy with natural orifice specimen extraction and review of the literature. Wideochir Inne Tech Maloinwazyjne. 2017 Sep;12(3):291-296. doi: 10.5114/wiitm.2017.69227. Epub 2017 Jul 27. PubMed 29062451 ↗
  • Kayaalp C, Kutluturk K, Yagci MA, Ates M. Laparoscopic right-sided colonic resection with transluminal colonoscopic specimen extraction. World J Gastrointest Endosc. 2015 Sep 10;7(12):1078-82. doi: 10.4253/wjge.v7.i12.1078. PubMed 26380054 ↗
  • Karagul S, Kayaalp C, Sumer F, Ertugrul I, Kirmizi S, Tardu A, Yagci MA. Success rate of natural orifice specimen extraction after laparoscopic colorectal resections. Tech Coloproctol. 2017 Apr;21(4):295-300. doi: 10.1007/s10151-017-1611-2. Epub 2017 Apr 26. PubMed 28447167 ↗
  • Awad ZT, Griffin R. Laparoscopic right hemicolectomy: a comparison of natural orifice versus transabdominal specimen extraction. Surg Endosc. 2014 Oct;28(10):2871-6. doi: 10.1007/s00464-014-3540-8. Epub 2014 May 2. PubMed 24789131 ↗
  • Gundogan E, Kayaalp C, Alinak Gundogan G, Sumer F. Total 102 natural orifice specimen extraction following laparoscopic colorectal resections. Updates Surg. 2023 Jan;75(1):197-203. doi: 10.1007/s13304-022-01412-4. Epub 2022 Nov 1. PubMed 36319790 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 20, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04394988
Lead sponsor
Inonu University
Responsible party
Ersin Gündoğan (Doctor- lecturer-Principal Investigator, Inonu University) — Principal investigator
First posted
May 20, 2020
Start date
Jan 1, 2013
Primary completion
Jul 30, 2018
Completion
Aug 1, 2018
Last update
May 20, 2020

Study contacts

Ersin Gundogan, MD
principal investigator · Inonu University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2020. You cannot join it, but the record below documents what was studied.

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