An observational study in Early Pregnancy and Ectopic Pregnancy, sponsored by Semra Yuksel. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 37 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-05-05.
Sponsored by Semra Yuksel · Observational
Among 13 studies in Pregnancy, Ectopic with a site in Turkey — 2 open to participants now, 2 under way, none of them phase 3. Pregnancy, Ectopic · Turkey.
Among the 13 studies in Pregnancy, Ectopic with a site in Turkey, this one is the only one that started in 2019, is one of 7 observational ones, and was the 8th registered.
83 studies on the registry are indexed under Pregnancy, Ectopic; 21 are open to participants now.
This study's enrollment of 88 is below the median of 150 across 39 observational studies indexed under Pregnancy, Ectopic.
Browse Pregnancy, Ectopic studies →2 of the 13 studies in Pregnancy, Ectopic with a site in Turkey are open now, in 1 country. Each count lists the studies.
Of the 10 Pregnancy, Ectopic studies recruiting now, 2 (20%) set no upper age limit and 8 (80%) stop at 75 or younger; 0 take children under 18; 1 take healthy volunteers.
This study: 18 Years to 37 Years · female · healthy volunteers too.
The full table on the hub →13 studies; the count open now beside each. This study's row is marked.
First in 2012; this study’s year is marked. 1 started in 2019.
Median enrollment 73 across the 6 interventional studies, 85 across the 7 observational. Of the 9 that completed or were terminated, 0 (0%) have results posted.
None of the 13 has an industry lead sponsor. The 9 most frequent:
This is the only study on the registry with Semra Yuksel as lead sponsor.
Semra Yuksel has 1 study filed under Pregnancy, Ectopic — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 13 studies in Pregnancy, Ectopic with a site in Turkey, from their registry updates:
Nothing recorded among them since 2026-09-25.
Kisspeptins are a family of neuropeptides that are critical for the puberty initiation and female fertility. The investigators aimed to investigate in this study kisspeptin levels in early pregnancy, ectopic pregnancy, and early pregnancy loss.
Clinicians can easily do a differential diagnosis of early pregnancy, miscarriage, and ectopic pregnancy when the human chorionic gonadotropin (hCG) values higher than 2000 mIU/mL with transvaginal ultrasound. However, in cases where the hCG value is below the critical threshold of 1500 to 2000 mIU/mL (often called the discrimination level) and ultrasound is not likely to be diagnostic, the pregnancy is of unknown location. Plasma or serum kisspeptin is mainly derived from the placenta during pregnancy and plasma kisspeptin levels significantly increase across pregnancy. Plasma kisspeptin levels could be used as a potential biomarker for the discrimination of miscarriage and ectopic pregnancy.
All statistics will be carried out with the use of SPSS (ver. 21, IBM). A P value of \<.05 is considered to be statistically significant. Pearson chi-square test will be used to evaluate between-group differences by pregnancy outcome for categoric data. Kisspeptin differences will be calculated between groups with one way ANOVA.
Women were considered for the study if they presented between 5-6 weeks of gestation by last menstrual period. Patients were included if they had either confirmed intrauterine pregnancy (IUP) by ultrasound (n=22) or confirmed miscarriage (SAB) by ultrasound (n=20) or ectopic pregnancy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Women aged between 18-37 years presented with between 5-6 weeks of gestation by last menstrual period.
Exclusion Criteria:
Ectopic pregnancy
Diagnostic Test: blood test
Early viable pregnancy
Diagnostic Test: blood test
incomplete miscarriage
Diagnostic Test: blood test
Healthy women
Diagnostic Test: blood test
blood test (serum samples) for biochemical examination
Kisspeptin levels in early pregnancy
Kisspeptin levels can be used for discrimination between ectopic pregnancy and incomplete miscarriage.
Time frame: January 2019-January 2020
Ran from Jan 2019 to primary completion in Aug 2019, 6 months.
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This study is completed, as verified in May 2020. You cannot join it, but the record below documents what was studied.
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