An observational study in Fever, Leukocytes and C Reactive Protein (CRP) is Less Than 20 mg/ l, sponsored by Gérond'if. Completed at 1 site in France. Open to participants aged 75 Years and older. Per ClinicalTrials.gov, last updated 2023-01-12.
Sponsored by Gérond'if · Observational
The main purpose of this monocentric, non-interventional, prospective study carried out in acute geriatrics (UGA) and post-rehabilitation care, is to determine if eosinopenia is associated with bacterial infections.
It's a monocentric, non-interventional, prospective study carried.
At inclusion:
Non-opposition will be collected by the investigator upon entering the Geriatric Unit.
The investigators will have all the biological and radiological results and will decide whether or not to start antibiotic treatment.
Patients will be divided into 2 groups: group with bacterial infections and the other with non-bacterial diseases.
The patient's socio-demographic data, reason for hospitalization, history, BMI, state of dependence (ADL-IADL), MMSE, treatments will be collected. Biological examinations in the phase where an infection is not suspected will also be collected (NFS, ionogram, urea, creatinemia, albumin, pre albumin, CRP, hepatocellular workup. Clinical examination during the episode may be infectious as well that biological and radiological data will be collected as well as the diagnosis made.
Antibiotic treatment is prescribed will be listed. The blood levels of eosinophils between the two groups will be compared.
Follow-up at 1 month:
The effectiveness of antibiotics will be evaluated on the absence of inflammatory syndrome and fever after the recommended antibiotic treatment and the duration of the recommended treatment. Vital status will be collected.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's enrollment of 156 is below the median of 240 across 2,136 observational studies indexed under Infections.
Browse Infections studies →Gérond'if is the lead sponsor of 35 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Subjects above 75 years of age, hospitalized in geriatrics.
Exclusion Criteria:
Patients with bacterial infection
Patients without bacterial infection
Determine if eosinopenia is associated with bacterial infections by measuring eosinophil counts.
Time frame: 1 month
Determine if eosinopenia is associated with the effectiveness of antibiotics by measuring eosinophil counts.
Time frame: 1 month
Determine if the eosinophil counts (PNE) / neutrophil (PNN)x1000 < 4 ratio is associated with a bacterial infection by measuring this value.
Time frame: 1 month
Determine if eosinopenia is associated with mortality by measuring eosinophil counts.
Time frame: 1 month
Determine if deep eosinopenia is associated with bacterial involvement by measuring if this value is less than 10 per mm3.
Time frame: 1 month.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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