Status unknownNCT04362020RAPID-2Updated May 12, 2020

Strategies to Maintain Radial Artery Patency Following Diagnostic Coronary Angiography - Subgroup of Patients on Oral Anticoagulants

An interventional study of Distal radial access and Distal radial access in Patient Undergoing Diagnostic Coronary Angiography, sponsored by University of Luebeck. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-05-12.

Sponsored by University of Luebeck · Not applicable, Interventional, and Prevention

The sponsor has not verified this record recently (last verified May 2020), so the status shown — last known as Not yet recruiting — may be out of date.

Phase: Not applicable
Study type: Interventional
Enrollment: 400
Allocation: Randomized
Ages: 18 Years and older
Sex: All

Study summary

To investigate whether omitting systemic anticoagulation during transradial coronary angiography and/or a distal radial access reduce the risk of postprocedural radial artery occlusion

Conditions studied

Patient Undergoing Diagnostic Coronary Angiography

In context

Lead sponsor

University of Luebeck is the lead sponsor of 74 studies on the registry; 13 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years and older
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

Clinical indication to perform diagnostic coronary angiography
Pretreatment with oral anticoagulants (phenprocoumon or direct oral anticoagulants [dabigatran, apixaban, rivaroxaban, or edoxaban])
Age > 18 years
Written informed consent

Exclusion criteria

Exclusion Criteria:

Already administered additional anticoagulation prior to coronary angiography
Planned coronary intervention
Preexisting radial artery occlusion or missing pulse at the potential puncture sites
Allergy / intolerance to anticoagulants
Active bleeding or comorbidity with elevated bleeding risk
Pregnancy
Inability to sign informed consent
Participation in another trial

Study design

Phase: Not applicable
Primary purpose: Prevention
Allocation: Randomized
Intervention model: Parallel assignment
Masking: None (open label)
Enrollment: 400 participants (estimated)

Study arms

Experimental
Group-1
No anticoagulation
Other: Distal radial access
Active comparator
Group-2
ACT-guided anticoagulation
Other: Distal radial access

Interventions

OtherDistal radial access
Distal radial access and No anticoagulation
OtherDistal radial access
Distal radial access and ACT-guided anticoagulation

What researchers measure

Primary outcomes

Occurrence of postprocedural radial artery occlusion
Will be the occurrence of postprocedural radial artery occlusion assessed with high-resolution vascular ultrasound. Experienced sonographers will perform color Doppler ultrasound in all study patients after removal of the compression device to examine the radial, ulnar, and brachial arteries of the access forearm.
Time frame: Day 1

Secondary outcomes

Sonographic characteristics of radial artery occlusion
Occlusion lengths or minimal residual perfusion
Time frame: 3 Month

Study locations

No study locations are listed for this record.

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on May 12, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT04362020
Lead sponsor: University of Luebeck
Responsible party: Prof. Dr. med. Ingo Eitel (Director, University of Luebeck) — Principal investigator
First posted: Apr 24, 2020
Start date: May 1, 2020 (estimated)
Primary completion: Nov 30, 2021 (estimated)
Completion: Aug 31, 2022 (estimated)
Last update: May 12, 2020

Oversight

Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2020. You cannot join it, but the record below documents what was studied.

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