CClinicalTrials.gg
CompletedNCT04360161Updated Apr 24, 2020

Observing the Morphology of Schlemm's Canal and Crystalline Lens in Different Age

An interventional study of swept-source optical coherence tomography in Schlemm's Canal Occlusion, sponsored by Wenzhou Medical University. Completed at 1 site in China. Open to participants aged 7 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-04-24.

Sponsored by Wenzhou Medical University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 8 months after the study started (first participant enrolled Aug 2019, registered Apr 2020).
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Not applicable
Ages
7 Years to 60 Years
Sex
All
01

Study summary

The aim of this study is to quantify and observe the morphology of trabecular meshwork (TM), Schlemm's canal (SC), ciliary body and crystalline lens before and after cycloplegia in patients with different ages using swept-source optical coherence tomography.

02

Conditions studied

  • Schlemm's Canal Occlusion
03

In context

Lead sponsor

Wenzhou Medical University is the lead sponsor of 93 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
7 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • healthy patients who can cooperated with the swept-source OCT measurements

Exclusion criteria

Exclusion Criteria:

  • history of ocular disease
  • presence of central nervous system or systemic disease
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
80 participants (actual)

Study arms

  • Experimental
    Healthy participants

    Swept-source optical coherence tomography A device testing TM/SC and Lens morphology

    Device: swept-source optical coherence tomography

Interventions

  • Deviceswept-source optical coherence tomography

    Aswe pt-source OCT (CASIA SS-1000; Tomey Corporation, Nagoya, Japan), which is specifically designed for anterior segment imaging using a 1310 nm wavelength with a scan speed of 30,000 A-scans per second and an axial resolution of \<10 μm.

06

What researchers measure

Primary outcomes

  1. area of Schlemm's canal and trabecular meshwork

    The area of Schlemm's canal and trabecular meshwork was manually measured and the relationship between the parameters and age was analyzed.

    Time frame: up to 6 months

07

Study locations

1 site
  • Eye Hospital of WMU
    Hangzhou, Zhejiang 325027, China
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 24, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04360161
Lead sponsor
Wenzhou Medical University
Responsible party
Yune Zhao (Director of Cataract Department, Wenzhou Medical University) — Principal investigator
First posted
Apr 24, 2020
Start date
Aug 8, 2019
Primary completion
Dec 20, 2019
Completion
Jan 20, 2020
Last update
Apr 24, 2020

Study contacts

Yune Zhao
study director · Eye Hospital of Wenzhou Medical University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2020. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion