An interventional study of Frequency comparison and Intensity comparison in Exercise Training, sponsored by Brendon Gurd, PhD. Status unknown at 1 site in Canada. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-03-04.
Sponsored by Brendon Gurd, PhD · Not applicable, Interventional, and Basic science
The purpose of this study is to compare the impact of augmenting exercise intensity and augmenting exercise frequency on peak work rate. Participants will complete exercise tests and provide 8 skeletal muscle samples following a within-subjects randomized crossover design utilizing single-leg cycling. Both training periods will be 4 weeks long and skeletal muscle biopsies will be collected from both legs before and after each training period. All exercise sessions will be supervised, take place in the investigator's laboratory, and occur on stationary bikes.
Brendon Gurd, PhD is the lead sponsor of 3 studies on the registry; none are open to participants now.
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Training period 1: Frequency comparison Training period 2: Intensity comparison
Behavioral: Frequency comparison · Behavioral: Intensity comparison
Training period 1: Intensity comparison Training period 2: Frequency comparison
Behavioral: Frequency comparison · Behavioral: Intensity comparison
One leg assigned to low-frequency low-intensity (3 days per week of 11 x 1 min @ 73% peak work rate interspersed with 1-minute periods of active recovery). The other leg assigned to high-frequency low-intensity (5 days per week of 11 x 1 min @ 73% peak work rate interspersed with 1-minute periods of active recovery).
One leg assigned to low-frequency low-intensity (3 days per week of 11 x 1 min @ 73% peak work rate interspersed with 1-minute periods of active recovery). The other leg assigned to low-frequency high-intensity (3 days per week of 8 x 1 min @ 100% peak work rate interspersed with 1-minute periods of active recovery).
Peak work rate
Change in Highest work rate achieved (30s period) during incremental exercise tests
Time frame: Before exercise training on two days (~7 and 6 days before first training session; ~24 hours apart), and after exercise on two days (~48-96 hours after the last training session; ~24 hours apart)
Peak oxygen uptake
Change in Highest oxygen uptake achieved (30s period) during incremental exercise tests
Time frame: Before exercise training on two days (~7 and 6 days before first training session; ~24 hours apart), and after exercise on two days (~48-96 hours after the last training session; ~24 hours apart)
Maximal citrate synthase activity
Change in maximal citrate synthase activity
Time frame: Before exercise training (~7 days before first training session), and after exercise training (~48-72 hours after the last training session)
Plan to share: No
No publications or documents are linked to this record.
Started Sep 2019 (actual). Primary completion is estimated for Apr 2020, 6 months after the start.
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This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
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Brendon Gurd, PhD