An observational study in Diaper Dermatitis, sponsored by Assiut University. Status unknown. Open to participants aged Up to 2 Years. Per ClinicalTrials.gov, last updated 2020-03-03.
Sponsored by Assiut University · Observational
Diaper dermatitis is one of the most common skin problems in infants and children.It is a skin disorder in the perineal , perianal and surrounding area .It frequently occurs also in areas immediately adjacent to the diaper area .
Diaper dermatitis is caused by lack of fresh air,dampness and irritation.With prevelance from 7-35 % in newborns.This skin disorder typically develops between nine and twelve months of age .
The development of diaper dermatitis is multifactorial . Newborn skin exhibits a cutaneous immaturity and an increased susceptibility toward skin barrier disruption or percutaneous absorption.
The epidermal barrier function resides in the outermost epidermal layer , the stratum corneum , which is the region of terminal skin differnatiation and is composed of corneocytes . The hydrophobic components of the lipid matrix provide the epidermal permeability barrier and protect against excessive water loss and irritant penetration , whereas the corneocytes and the cornified envelope provide mechanical strength to the stratum corneum.
The skin in the diaper area is predisposed to irritation by the prolonged contact with irritants , such as urine and feces as well as by diaper occlusion, with leads to an increase in hydration and skin ph. Overhydration promotes degradation of "the brick and mortar" structure of stratum corneum, contributing to impraired barrier function.
1,435 studies on the registry are indexed under Dermatitis; 131 are open to participants now.
This study's planned enrollment of 50 is below the median of 100 across 232 observational studies indexed under Dermatitis.
Browse Dermatitis studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
the out patient clinic of department of dermatology,venereology and andrology , Assuit university .
Exclusion Criteria:
The percentage of patients with risk factors for Diaper dermatitis
The percentage of patients with breastfeeding, presence of diarrhea, and frequency of diaper change
Time frame: One week
No study locations are listed for this record.
This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
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Assiut University