An observational study in Venous Leg Ulcer, sponsored by University Hospital of Limerick. Completed at 1 site in Ireland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-12-15.
Sponsored by University Hospital of Limerick · Observational
This Study aims to identify whether venous leg ulcers which are colonised by Pseudomonas Aeruginosa cause more pain than those which are not and if this bacteria affects healing time. This may determine how venous ulcer infections are treated in order to improve symtomatology and quality of life for patients with these chronic wounds.
Pseudomonas is a gram-negative bacillus which commonly colonises lower limb venous ulcers. It produces exotoxins and elastase as well as forming biofilms within chronic wounds.
Its effects on venous ulcer healing are debated. The objective of this study is to examine the effects on Pseudomonas Aeruginosa colonisation on the pain expereinces and healing rates of venous leg ulcers.
384 studies on the registry are indexed under Varicose Ulcer; 80 are open to participants now.
This study's enrollment of 100 is below the median of 150 across 41 observational studies indexed under Varicose Ulcer.
Browse Varicose Ulcer studies →University Hospital of Limerick is the lead sponsor of 16 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Vascular patients with new and old venous ulcers to their lower limbs. As deemed suitable as per the inclusion/exclusion criteria. As deemed suitable by the P.I.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Pain burden of venous ulcers colonised by Pseudomonas Aeruginosa
Pain will be examined with respect to underlying microbiota detected by wound culture and sensitivity. The Brief Pain Inventory (Short Form) will be used for assessment purposes.
Time frame: 1 year
Presentations and Admissions
Rates of re-presentation for treatment with respect to underlying wound culture and sensitivity. Number of patient visits to the Vascular Clinic for treatment will be measured.
Time frame: 1 year
Analgesia Requirements
Number of participants with pain requiring analgesia will be recorded.
Time frame: 1 year
Plan to share: Undecided
No publications or documents are linked to this record.
Ran from Jan 2020 to primary completion in Dec 2023, 47 months.
Of 23 observational studies under Varicose Ulcer, half reached primary completion within 31 months of starting (the median), counting those still running; a quarter within 16. This study's 47 months is above that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2023. You cannot join it, but the record below documents what was studied.
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University Hospital of Limerick