An interventional study of Optimisation of DTI sequences in Radiculopathy Lumbar, MRI and Diffusion Tensor Imaging, sponsored by Lille Catholic University. Completed at 1 site in France. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-02-03.
Sponsored by Lille Catholic University · Not applicable, Interventional, and Diagnostic
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots. DTI is a widely used neuroimaging technique and is a current topic of research in the field of peripheral nerve imaging. The aim of this work is therefore to improve DTI sequences by specifically evaluating the contribution of the multiband technique in healthy volunteers.
For every healthy volunteer will be acquired:
488 studies on the registry are indexed under Radiculopathy; 141 are open to participants now.
This study's enrollment of 20 is below the median of 60 across 376 interventional studies indexed under Radiculopathy.
Browse Radiculopathy studies →Lille Catholic University is the lead sponsor of 111 studies on the registry; 26 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Healthy volunteers
Diagnostic Test: Optimisation of DTI sequences
Optimisation of DTI sequences in the study of lumbar roots by MRI
Image quality measured as signal-to-noise ratio and contrast-to-noise ratio
Comparison of the image quality between DTI optimized and DTI of reference. The signal-to-noise ratio is a measure that compares the level of a desired signal to the level of background noise. Mathematically, the signal-to-noise ratio is the quotient of the (mean) signal intensity measured in a region of interest and the standard deviation of the signal intensity in a region outside the anatomy of the object being imaged. The contrast-to-noise ratio is a measure of image quality based on a contrast rather than the raw signal.
Time frame: Day 0
Fraction of anisotropy and apparent diffusion coefficient
Comparison of fraction of anisotropy, and apparent diffusion coefficient between DTI optimized and DTI of reference. The measurement of fraction of anisotropy, and apparent diffusion coefficient provides robust values for quantifying the degree of microstructural abnormalities of nerves.
Time frame: Day 0
Concordance of observed agreement measured by Cohen's kappa coefficient
Evaluation of interobserver accordance for multiband acquisitions (optimized DTI)
Time frame: Day 0
Concordance of observed agreement measured by Intra-class correlation coefficient
Evaluation of interobserver accordance for multiband acquisitions (optimized DTI)
Time frame: Day 0
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Lille Catholic University