An observational study in Gut Health, sponsored by University Hospital, Lille. Recruiting at 1 site in France. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-07.
Sponsored by University Hospital, Lille · Observational
The aim of the study is to evaluate the impact of early nutrition on gut health in children. A prospective cohort of newborns will be recruited at birth and followed up to 4 years of age. Information on parent's nutritional habits and life style, breastfeeding duration and child's complementary feeding, will be collected. Cord blood cells and stools will be collected at birth, 6 months, 2 years and 4 years of age for implementing a biological collection. Gut health will be evaluated in children during the first four years of life based on fecal secretory immunoglobulin A (SIgA) and presence of digestive symptoms. Precise data on breastfeeding practices and their short- and medium-term effects on the health of the child, in particular and in an innovative way on gut health, will be obtained.
262 studies on the registry are indexed under Breast Feeding; 112 are open to participants now.
This study's planned enrollment of 500 is above the median of 177 across 48 observational studies indexed under Breast Feeding.
Browse Breast Feeding studies →University Hospital, Lille is the lead sponsor of 625 studies on the registry; 141 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Monocentric cohort including mother/child dyads recruited in a University Maternity
For the mother:
For the father:
Exclusion Criteria:
For the mother:
For the child after birth:
Correlation between exclusive breastfeeding and gut health based on the non-invasive measurement of fecal secretory immunoglobulin A (sIgA)
Time frame: AT 4 years
Correlation between gut health and the duration of exclusive breastfeeding
defined by the production of Igas in the faeces and the duration of exclusive breastfeeding (1 month, 1-2 months, 2-4 months, 4-6 months, 6 months) collected by mother's interrogation.
Time frame: A 1 month, 1-2 months, 2-4 months, 4-6 months, 6 months
Correlation between the mother's feeding habits during pregnancy and the child's gut health during the first 4 years of life
Nutritional data collected via the Food Frequency Questionnaire (FFQ) and the mother's obstetric record and Intestinal health of the child during the first 4 years of life evaluated by the production of Igas
Time frame: At 6 months, 2 years and 4 years
Correlation between sIgA and child growth and gastro-intestinal disorders
defined by Production of Igas in children and the head circumference, weight and height of the child reported in the health log and the presence of gastrointestinal symptoms evaluated according to the criteria of ROME IV.
Time frame: At 6 months, 2 years and 4 years
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University Hospital, Lille