An interventional study of Olive oil and Butter in Cardiovascular Risk Factor, sponsored by Northumbria University. Status unknown at 1 site in United Kingdom. Open to male participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-03-17.
Sponsored by Northumbria University · Not applicable, Interventional, and Treatment
The main aim of this study is to examine the effect of olive oil consumption on several cardiovascular risk markers between Caucasians and Asian ethnicity. The primary assessments: endothelial function's biomarkers: cell and vascular adhesion molecules (ICAMs and VCAMs) and nitric oxide (NO). The secondary assessments: Lipid profile.
Northumbria University is the lead sponsor of 160 studies on the registry; 22 are open to participants now.
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Male
Orient Asians (including Chinese, Japanese, Korean, and Malaysia Chinese) and Caucasians
Age 18-70 years
Self-reported in good general health
Exclusion Criteria:
Female
Age older than 70 years or younger than 18 years
Diagnosed and/or are taking medications for hypertension (>140/90mmHg)
Diabetes
High blood cholesterol
Heart problems (e.g. arrhythmia, high-grade stenosis of the carotid artery or carotid sinus syndrome)
Allergy to olive oil or olive oil products
Lactose intolerance
Taking omega-3 supplements in fish oil and vitamins supplements in the last six months.
Participants will receive 30ml/day of olive oil for two weeks
Dietary Supplement: Olive oil · Dietary Supplement: Butter
Participants will receive 30g/day of butter also for two weeks.
Dietary Supplement: Olive oil · Dietary Supplement: Butter
Participants will be randomly allocated to receive daily dose of 30ml of olive oil (OO) as intervention group or a matching control (butter 30g) for 2 weeks each (i.e. two weeks olive oil and two weeks butter), separated by a washout period of 2 weeks between treatments.
Participants will be randomly allocated to receive daily dose of 30ml of olive oil (OO) as intervention group or a matching control (butter 30g) for 2 weeks each (i.e. two weeks olive oil and two weeks butter), separated by a washout period of 2 weeks between treatments.
changes in ambulatory blood pressure
Time frame: Baseline and 2 weeks
Changes in plasma total cholesterol
Plasma total cholesterol vascular cell adhesion molecule 1
Time frame: Baseline and 2 weeks
Changes in Intercellular Adhesion Molecule 1
Plasma levels of Intercellular Adhesion Molecule 1 measured
Time frame: Baseline and 2 weeks
Changes in vascular cell adhesion molecule 1
Plasma levels of vascular cell adhesion molecule 1 measured
Time frame: Baseline and 2 weeks
Changes in C-reactive protein
Plasma levels of CRP measured
Time frame: Baseline and 2 weeks
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Olive Oil