An interventional study of Bronchoscopy and Ultrasound-Guided Transbronchial Needle Aspiration in Lung Carcinoma, sponsored by Ohio State University Comprehensive Cancer Center. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-01.
Sponsored by Ohio State University Comprehensive Cancer Center · Not applicable, Interventional, and Diagnostic
This trial studies how well endobronchial ultrasound-guided transbronchial needle-aspiration (EBUS-TBNA) with suction works in obtaining samples from patients with suspected lung cancer that has spread to the nodal. EBUS-TBNA samples obtained with additional suction may help to improve material-amounts and decrease blood contamination in the samples.
PRIMARY OBJECTIVES:
I. To evaluate if suction applied with a vacuum syringe during EBUS-TBNA sampling helps to obtain more material for molecular analyses.
OUTLINE:
Patients undergo bronchoscopy with EBUS-TBUA first without and then with applied vacuum.
7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.
This study's enrollment of 50 is below the median of 60 across 5,295 interventional studies indexed under Lung Neoplasms.
Browse Lung Neoplasms studies →Ohio State University Comprehensive Cancer Center is the lead sponsor of 369 studies on the registry; 81 are open to participants now.
Of its 38 completed or terminated interventional studies of FDA-regulated products, 19 (50%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients undergo bronchoscopy with EBUS-TBUA first without and then with applied vacuum.
Procedure: Bronchoscopy · Procedure: Ultrasound-Guided Transbronchial Needle Aspiration
Undergo bronchoscopy with EBUS-TBNA
Undergo bronchoscopy with EBUS-TBNA
Also known as: EBUS-TBNA, Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Number of samples collected via endobronchial ultrasound-guided transbronchial needle-aspiration with suction
The qualitative data will have a set number of variable to follow and will be converted to quantitative data. Data will be analyzed using Microsoft Excel, SAS, or SPSS. After checking the normality of the data, all non-parametric data will be converted to parametric data. Appropriate tests for categorical and continuous data will be used. Categorical variables will be compared using Chi-square or Fisher?s Exact test. Normally distributed variables will be compared using Student-T-test and one way analysis of variance. Non-parametric test will include Mann Whitney U test and Kruskal Wallis test. A two tailed p value of \< 0.05 will be considered significant.Sample weight (microgram) and visual blood contamination score (0 = no visible blood, 1 = light red shading, 2 = red shading) of endobronchial needle aspiration biopsies obtained with and without suction.
Time frame: Up to 3 years
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Plan to share: No
This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Ohio State University Comprehensive Cancer Center