An interventional study of Low-level Laser Therapy and Orthodontic force in Laser Therapy, Orthodontic Tooth Movement and Bone Remodeling, sponsored by Ildeu Andrade Jr.. Completed at 1 site in Brazil. Open to participants aged 13 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-09-24.
Sponsored by Ildeu Andrade Jr. · Not applicable, Interventional, and Treatment
The aims of this study will be to evaluate if a Lower Level Laser Therapy (LLLT): (1) enhances the levels of important pro-inflammatory chemokines involved in the bone remodeling process; (2) increases the rate of orthodontic tooth movement (OTM) on human subjects.
Ildeu Andrade Jr. is the lead sponsor of 2 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
No orthodontic force. Laser is applied on the first day and the premolars is extracted after 24 hours
Device: Low-level Laser Therapy
Orthodontic force and Laser is applied on the first day and the premolars is extracted after 24 hours
Device: Low-level Laser Therapy · Procedure: Orthodontic force
Orthodontic force is applied and the premolars is extracted after 24 hours, with no laser therapy
Procedure: Orthodontic force
Orthodontic force and Laser is applied and the orthodontic tooth movement is evaluated
Device: Low-level Laser Therapy · Procedure: Orthodontic force
Orthodontic force is applied and the orthodontic tooth movement is evaluated, with no laser therapy
Procedure: Orthodontic force
Low-level laser therapy is applied on premolars that will be extracted for treatment plan reasons
Mechanical loading is applied on premolars that will be extracted for treatment plan reasons and in canines for tooth movement
Rate of orthodontic tooth movement, with and without low-level laser therapy
The canine retraction was measured with a digital dynamometer
Time frame: The quantification of OTM was performed before canine retraction
Rate of orthodontic tooth movement, with and without low-level laser therapy
The canine retraction was measured with a digital dynamometer
Time frame: The quantification of OTM was performed after 1 month of canine retraction
Rate of orthodontic tooth movement, with and without low-level laser therapy
The canine retraction was measured with a digital dynamometer
Time frame: The quantification of OTM was performed after 2 months of canine retraction
Rate of orthodontic tooth movement, with and without low-level laser therapy
The canine retraction was measured with a digital dynamometer
Time frame: The quantification of OTM was performed after 3 months of canine retraction
Chemokine levels in the periodontal tissue after LLLT and orthodontic force
The chemokine levels were measured in the periodontal tissue after LLLT and orthodontic force by means of a cytometric bead array (CBA)
Time frame: The chemokine levels were assayed on days 0, 1, 7 and 14 after application of orthodontic force and low-level laser therapy
Plan to share: No
This study is completed, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.
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Ildeu Andrade Jr.