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CompletedNCT04050774BaCoMechUpdated Aug 3, 2022

Standing Balance Control Across the Lifespan

An interventional study of Balance boards in Children, Adult, sponsored by Hasselt University. Completed at 1 site in Belgium. Open to participants aged 6 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-08-03.

Sponsored by Hasselt University · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Registered 8 months after the study started (first participant enrolled Nov 2018, registered Aug 2019).
Phase
Not applicable
Study type
Interventional
Enrollment
41
Allocation
Non-randomized
Ages
6 Years to 80 Years
Sex
All
01

Study summary

Falls are the leading cause of nonfatal injuries in children and elderly. To understand the causes of falling in these populations, fundamental knowledge of how ageing affects balance control is of utmost importance.

In general, two biomechanical mechanisms allow people to control balance; 1.moving the center of pressure within the base of support using ankle muscle activation; 2.counter-rotating segments around the center of mass. To understand how balance is controlled differently across the lifespan, 4 age groups (each N=20) will be compared to each other; i.e. prepubertal children (6-9y), postpubertal children (15-17y), young adults (18-24y), healthy non-falling older adults (65-80y). .

A force plate platform combined with 3D movement registration will be used to determine the biomechanical balance control strategy across the lifespan during unperturbed and perturbed standing. The innovative but focused scope of this study could provide a breakthrough in our biomechanical understanding of balance control and, in particular, the changes in limitations of balance control in childhood and an ageing (fall-prone) population. The gained fundamental knowledge could lead to unprecedented insights in the causes of falling across the lifespan and in possible targets for intervention.

02

Conditions studied

  • Children, Adult
03

In context

Lead sponsor

Hasselt University is the lead sponsor of 195 studies on the registry; 30 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • prepubertal children (6-9y)
  • postpubertal children (15-18y)
  • young adults (18-24y)
  • healthy non-falling older adults (65-80y) will be included if they 1) did not experience two or more falls during normal daily activities in the preceding year and 2) have no cognitive impairment (tested with Mini-Mental state examination).

Exclusion criteria

Exclusion Criteria:

  1. inability to speak and understand Dutch;
  2. inability to maintain independent unsupported stance for 60 seconds;
  3. current diagnosis of neurological or sensory disorders;
  4. recurrent dizziness;
  5. obesity ;
  6. a history of orthopaedic disorders;
  7. surgical operation of the lower extremity during last two years;
  8. use of drugs affecting the CNS or known to affect balance control.
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
41 participants (actual)

Study arms

  • Experimental
    Age group 1

    6-9 years old

    Device: Balance boards

  • Experimental
    Age group 2

    15-17 years old

    Device: Balance boards

  • Experimental
    Age group 3

    18 - 24 years old

    Device: Balance boards

  • Experimental
    Age group 4

    65-80 years old

    Device: Balance boards

Interventions

  • DeviceBalance boards

    The unstable surface will be created with a balance board consisting of a wooden board mounted on a section of a cylinder, creating an unstable support in the sagittal plane or in the frontal plane. The participants will stand on three balance boards, varying the height of the surface of the board above the point of contact (15, 17 and 19 cm respectively). The radius of the cylinder will kept constant at 24 cm. The standing surface will be 48cm x 48 cm

06

What researchers measure

Primary outcomes

  1. Balance Control; centre of mass acceleration based on 3D movement registration and ground reaction forces

    Centre of mass acceleration (in kg.m2/s2) (calculations based on; van Dieen JH, van Leeuwen M, Faber GS. Learning to balance on one leg: motor strategy and sensory weighting. J Neurophysiol. 2015;114(5):2967-82.)

    Time frame: day 1

  2. Contribution of the ankle strategy to centre of mass acceleration based on 3D movement registration and ground reaction forces

    The contribution of the ankle strategy (difference between the centre of pressure and the centre of mass (in kg.m2/s2)) to centre of mass acceleration in the sagittal and frontal plane will be calculated based on total body kinematics (SIMI motion - 3D movement registration) and kinetics (AMTI force plate) (calculations based on; van Dieen JH, van Leeuwen M, Faber GS. Learning to balance on one leg: motor strategy and sensory weighting. J Neurophysiol. 2015;114(5):2967-82.)

    Time frame: day 1

  3. Contribution of the counter-rotation mechanism to centre of mass acceleration based on 3D movement registration and ground reaction forces

    The contribution of the counter-rotation mechanism (change in angular momentum (in kg.m2/s2)) to centre of mass acceleration in the sagittal and frontal plane will be calculated based on total body kinematics (SIMI motion - 3D movement registration) and kinetics (AMTI force plate) (calculations based on; van Dieen JH, van Leeuwen M, Faber GS. Learning to balance on one leg: motor strategy and sensory weighting. J Neurophysiol. 2015;114(5):2967-82.))

    Time frame: day 1

07

Study locations

1 site
  • Hasselt University
    Hasselt, 3500, Belgium
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 3, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04050774
Lead sponsor
Hasselt University
Collaborators
VU University of Amsterdam
Responsible party
Pieter Meyns (Principal Investigator, Hasselt University) — Principal investigator
First posted
Aug 8, 2019
Start date
Nov 21, 2018
Primary completion
Apr 1, 2021
Completion
Apr 1, 2021
Last update
Aug 3, 2022

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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