An observational study in Infant Behavior, Infant Conditions and Infant Morbidity, sponsored by Ospedale di Circolo - Fondazione Macchi. Completed at 1 site in Italy. Open to participants aged 1 Day to 90 Days. Per ClinicalTrials.gov, last updated 2026-05-26.
Sponsored by Ospedale di Circolo - Fondazione Macchi · Observational
AIM: to investigate the influence of different music genres on Heart Rate Variability (HRV) of preterm infants.
Neonates undergo a daily randomized music listening program. An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.
AIM: to investigate the influence of different music genres on Heart Rate Variability (HRV) of preterm infants.
HRV has been previously used to evaluate autonomic nervous system fluctuations in heart rate related to maturation in healthy neonates and in neonates with pathological conditions. This parameter has been used to show how music could improve well-being and the development of the autonomic nervous system in infants.
In this study, neonates (see also inclusion/exclusion criteria), recruited on the basis of birth order, undergo a daily randomized music listening program (25 minutes, every day, for 3 days) based on different music genres listening (soft pop-rap, pop-rock and classical music). Music programs is followed by 1 day of no music monitoring (25 minutes). An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.
37 studies on the registry are indexed under Infant Behavior; 5 are open to participants now.
Browse Infant Behavior studies →Ospedale di Circolo - Fondazione Macchi is the lead sponsor of 13 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Enrollment performed when sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the test
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Exclusion Criteria:
Neonates undergo a daily randomized music listening program (25 minutes, every day, for 3 days) based on different music genres listening (soft pop-rap, pop-rock and classical music). Music programs is followed by 1 day of no music monitoring (25 minutes). An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure
Heart Rate Variability (HRV) variation in preterm infants according to different music genres listening
An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.
Time frame: Enrollment performed when sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the treatment
Ran from Feb 2019 to primary completion in Jun 2019, 4 months.
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This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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Ospedale di Circolo - Fondazione Macchi