An interventional study of duration of standard antibiotic therapy in Infection, sponsored by Balgrist University Hospital. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-24.
Sponsored by Balgrist University Hospital · Not applicable, Interventional, and Treatment
We implement a prospective, randomized, unblinded, non-inferiority trial regarding the duration of systemic, targeted antibiotic therapy after the first surgical debridement for spine infection; randomizing 1:1 between
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's enrollment of 271 is above the median of 120 across 4,200 interventional studies indexed under Infections.
Browse Infections studies →Balgrist University Hospital is the lead sponsor of 80 studies on the registry; 14 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
3 weeks of antibiotic therapy with no implant left in place 6 weeks of antibiotic therapy with implant left in place
Drug: duration of standard antibiotic therapy
6 weeks of antibiotic therapy with no implant in place 12 weeks of antibiotic therapy with implant left in place
Drug: duration of standard antibiotic therapy
antibiotic therapy for spine infections. 3 vs 6 weeks if no implant left in place. 6 vs 12 weeks if implant left in place. The antibiotic agents used are officially indicated for orthopedic infections, including spine infections and available in Switzerland since decades. Standard dosing will be applied and only modified according to the patient's co-morbidities, intolerances and weight.
Also known as: Co-amoxiclav, vancomycin
Remission of infection at 12 months after treatment
no clinical and microbiological recurrences
Time frame: 12 months after treatment
costs
total costs for treatment of infection
Time frame: up to 12 months
duration of sick leave
duration of sick leave for treatment of infection
Time frame: up to 12 months
length of hospital stay
number of days of hospital stay
Time frame: up to 12 months
Documents are hosted by the registry — open the source record to download them.
Plan to share: No — identifying IPD will not be shared with other Researchers
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Balgrist University Hospital