A Phase 4 interventional study of Bleomycin and Saline Solution in SCAR, sponsored by Clinica Dermatologica Arbache ltda. Status unknown at 1 site in Brazil. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2019-08-06.
Sponsored by Clinica Dermatologica Arbache ltda · Phase 4, Interventional, and Treatment
This intervention, called MMP®, is a procedure whereby drugs are injected through tattoo machines.
Treatment consists of Bleomycin infusion (3.0 U/ml) compared to saline infusion (parallel treatment).
Results will be evaluated after a maximum of 7 treatments, through clinical evaluation and Antera equipment analyze.
Laboratory tests are being requested to verify hematologic, renal and hepatic integrity.
The treatment will be double blind, one side of the scar will be treated with bleomycin and the other side saline infusion.
The test will consist of 5 subgroups of scars:
Therefore, the total will be 50 participants.
611 studies on the registry are indexed under Cicatrix; 114 are open to participants now.
This study's planned enrollment of 50 is above the median of 40 across 512 interventional studies indexed under Cicatrix.
Browse Cicatrix studies →Clinica Dermatologica Arbache ltda is the lead sponsor of 5 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Bleomycin Infusion By Tattoo Machine
Drug: Bleomycin · Other: Saline Solution
Saline Infusion by Tattoo Machine
Drug: Bleomycin · Other: Saline Solution
Skin bleomycin infusion through tattoo machine
Saline solution infusion through tattoo machine
Level of melanin in the achromic scars (scar repigmentation)
Investigators will use antera device to measure the level of melanin in the achromic scars and photografic documentation
Time frame: Measured at baseline and up to four months after treatment
Treatment-Emergent Adverse Events of bleomycin infusion into the skin
Treatment-Emergent Adverse Events assessment through clinical follow-up and photographic documentation
Time frame: 11 monts
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Aug 2019; primary completion for Aug 2020, 12 months later.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Bleomycin
Clinica Dermatologica Arbache ltda