An observational study in Pupillary Functions, Abnormal, sponsored by Seoul National University Hospital. Status unknown at 1 site in Korea, Republic of. Open to participants aged 3 Years to 12 Years. Per ClinicalTrials.gov, last updated 2020-08-17.
Sponsored by Seoul National University Hospital · Observational
To compare of effects of volatile and intravenous anesthetics on pupillary function during general anesthesia in children
The investigator will measure the pupillary function with pupillometry during general anesthesia with volatile or intravenous anesthetics in children.
Seoul National University Hospital is the lead sponsor of 1,860 studies on the registry; 275 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.
Counted across the registry records on this site, refreshed daily.
From other study results, average NPi for Sevoflurane and propofol were 3.6, 4.2, and standard deviation was 0.1, 0.4 respectively. Using Gpower program, total of 18 patients were required. Considering 20% of drop-out rate, total of 22 patients(18+3.6 patients) were to be recruited.
Exclusion Criteria:
Using inhalent agent(Sevoflurane), continuous infusion of Remifentanil
Other: sevoflurane
Using continuous infusion of Propofol and Remifentanil
Other: propofol
volatile anesthetic
intravenous anesthetic
NPi
Neurological Pupil index
Time frame: 1hour afer skin incision
%CH
% change of pupil size
Time frame: 1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubation
CV
Constriction Velocity
Time frame: 1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubation
DV
Dilation Velocity
Time frame: 1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubation
NPi
Neurological Pupil index
Time frame: 1. Stage of loss of consciousness after induction with bolus propofol 2. Before and after tracheal intubation 3. Skin incision 4. 1hour afer skin incision 5. Just before extubation
Plan to share: No
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This study is status unknown, as verified in Aug 2020. You cannot join it, but the record below documents what was studied.
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Pupil Disorders
Seoul National University Hospital