CClinicalTrials.gg
RecruitingNCT03956602Updated Jan 21, 2026

Effects of Snack Types on Acute Glucose and Insulin Response

An interventional study of Pretzels and Brazil nuts in Satiety, sponsored by San Diego State University. Recruiting at 1 site in United States. Open to participants aged 18 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-21.

Sponsored by San Diego State University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 1 year 3 months after the study started (first participant enrolled Jan 2018, registered Apr 2019).
  • Started Jan 2018; still recruiting 8 years 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
160
Allocation
Randomized
Ages
18 Years to 55 Years
Sex
All
01

Study summary

The purpose of the present study was to determine the effects of different type of snack consumption on postprandial satiety, glucose, insulin, antioxidant capacity and anxiety in healthy subjects.

02

Conditions studied

  • Satiety
03

In context

Lead sponsor

San Diego State University is the lead sponsor of 145 studies on the registry; 41 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • 18-55 years old

Exclusion criteria

Exclusion Criteria:

  • Smoker
  • Pregnant woman
  • Required dietary supplement use
  • Required medication of metabolic disorders
  • Allergy to nuts or gluten (wheat)
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
160 participants (estimated)

Study arms

  • Active comparator
    Pretzels

    Subjects consume pretzels to examine postprandial response

    Other: Pretzels

  • Experimental
    Brazil nuts

    Subjects consume Brazil nuts to examine postprandial response

    Other: Brazil nuts

  • Active comparator
    Potato chips

    Subjects consume potato chips to examine postprandial response

    Other: Potato chips

  • Experimental
    Mixed nuts

    Subjects consume mixed nuts to examine postprandial response

    Other: Mixed nuts

  • Active comparator
    White bread

    Subjects consume white bread to examine postprandial response

    Other: White bread

  • Experimental
    Dried mango

    Subjects consume dried mango to examine postprandial response

    Other: Dried mango

  • Experimental
    Mango fruit

    Subjects consume fresh mango to examine postprandial response

    Other: Mango fruit

Interventions

  • OtherPretzels

    To examine postprandial responses of pretzel consumption

  • OtherBrazil nuts

    To examine postprandial responses of Brazil nut consumption

  • OtherPotato chips

    To examine postprandial responses of potato chip consumption

  • OtherMixed nuts

    To examine postprandial responses of mixed nut consumption

  • OtherWhite bread

    To examine postprandial responses of white bread consumption

  • OtherDried mango

    To examine postprandial responses of dried mango consumption

  • OtherMango fruit

    To examine postprandial responses of fresh mango consumption

06

What researchers measure

Primary outcomes

  1. Change of Satiety

    Hunger feeling (appetite) will be examined using visual analog scale (0-10): 0 least and 10 greatest

    Time frame: 0, 20, 40, 60, 90 and 120 minutes post snack consumption

  2. Change of glucose level

    Blood will be collected by finger pricks and change of glucose level will be examined.

    Time frame: 0 and 40 minutes post snack consumption

  3. Change of insulin level

    Blood will be collected by finger pricks and change of insulin level will be examined

    Time frame: 0 and 40 minutes post snack consumption

  4. Change of anxiety feeling

    Anxiety feeling will examined using STAI (Spielberger Stasumte-Trait Anxiety Inventory) questionnaire (1-4): 1 least and 4 greatest, total summed score will be used.

    Time frame: 0 and 40 minutes post snack consumption

  5. Change of antioxidant level

    Blood will be collected by finger pricks and change of antioxidant level will be examined

    Time frame: 0 and 40 minutes post snack consumption

07

Study locations

1 of 1 sites recruiting
  • School of Exercise and Nutritional Sciences, SDSU
    San Diego, California 92182-7251, United States
    Recruiting
08

References and documents

Publications

  • Stamper C, Safadi S, Gehr A, Asuncion P, Hong MY. Effects of fresh vs dried mango consumption on satiety and postprandial glucose in healthy adults. Metabol Open. 2023 Jul 18;19:100253. doi: 10.1016/j.metop.2023.100253. eCollection 2023 Sep. PubMed 37520177 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 21, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03956602
Lead sponsor
San Diego State University
Responsible party
Sponsor
First posted
May 20, 2019
Start date
Jan 15, 2018
Primary completion
Dec 2028 (estimated)
Completion
Dec 2028 (estimated)
Last update
Jan 21, 2026

Study contacts

Mee Young Hong
Contact
mhong2@sdsu.edu
6195942392

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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