An observational study in Diabetes Mellitus and Exercise, sponsored by King Saud University. Completed. Open to participants aged 45 Years to 70 Years. Per ClinicalTrials.gov, last updated 2019-04-24.
Sponsored by King Saud University · Observational
To elucidate the potential role of exercise as anti-adiposity and anti-cardio protective modulates, we thought to investigate the effect of supervised aerobic training of moderate intensity on adiposity markers, nitric oxide level, plasma adiponectin, hs-CRP, and its association with CHD risk score in obese and non-obese patients with type 2 diabetes.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's enrollment of 50 is below the median of 233 across 2,220 observational studies indexed under Diabetes Mellitus.
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Fifty subjects diagnosed with type 2 diabetes for more than 5 years aged 45-70 years were invited in the period from 2013 to 2014 to participate in this study. Patients were diagnosed according to the criteria of American diabetes association.32 Based on the values of BMI, the patients were classified into two groups, obese diabetic group (n= 25, BMI ≥ 30 kg/m2) and non-obese group (n= 25, BMI ≤ 30 kg/m2).
Exclusion Criteria:
non-obese diabetic patients (n= 25, BMI ≤ 30 kg/m2) were subjected to supervised aerobic exercise
obese diabetic group (n= 25, BMI ≥ 30 kg/m2)
Other: Supervised aerobic exercise
Estimation of coronary heart disease risk score
The incidence risk score of coronary heart disease among type 2 diabetic participants .patients were classified into T2DM patients with high CHD risk (UKPDS risk ; ≥ 20%), moderate CHD risk (UKPDS risk ; 10-20%), and low (UKPDS risk;\< 10%) .
Time frame: six months
Analysis of blood sugar, glycated hemoglobin (HbA1c)
Blood glucose was measured using a glucose oxidase and peroxidase (GOD-POD) colorimetric method before and after exercise training
Time frame: six months
Analysis of Nitric Oxide
Plasma NO concentration was estimated as nitrate and nitrite using High Performance Liquid Chromatography technology (HPLC). Patients were subjected for nitri oxide analysis before and after exercise training interventions
Time frame: six months
No study locations are listed for this record.
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King Saud University