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CompletedNCT03879499Updated Jul 18, 2024

Postoperative CRP Levels and Vaginal Cuff Hematoma

An observational study in Postoperative Hematoma, sponsored by Kanuni Sultan Suleyman Training and Research Hospital. Completed. Open to female participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-07-18.

Sponsored by Kanuni Sultan Suleyman Training and Research Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
106
Ages
40 Years to 65 Years
Sex
Female
01

Study summary

After laparoscopic hysterectomy, authors aimed to determine cuff hematoma and a postoperative CRP value to help predict the other complications.

A total of 136 patients who underwent total laparoscopic hysterectomy (TLH) were evaluated. CRP, White blood cell (WBC) and hemoglobin values (Hb) were measured on the 1st, 2nd and 7th days before and after the operation. Complications, pre-postoperative vaginal length and female sexual function were evaluated. Fourteen patients who developed cuff hematoma during postoperative follow-up were analyzed with the receiver operating characteristics (ROC) curve. ROC curves with the largest area under the curve for each inflammatory marker were compared in order to define the marker with higher diagnostic accuracy.

02

Conditions studied

  • Postoperative Hematoma

Keywords

  • cuff hematoma
  • CRP levels
03

In context

Lead sponsor

Kanuni Sultan Suleyman Training and Research Hospital is the lead sponsor of 224 studies on the registry; 34 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 65 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

women who underwent TLH operation with benign gynecological indications

Eligibility criteria

Inclusion Criteria:women who underwent TLH operation with benign gynecological indications

Exclusion Criteria:

  • Decided to switch to laparotomy during operation
  • postoperative complication due to relaparotomy
  • infection (including urinary system and lung infections)
  • Blood transfusion after TLH
  • with rheumatic diseases
  • length of hospital stay due to wound infection
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
106 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Relationship between CRP Levels and cuff hematoma; crp levels

    The value of Postoperative CRP Levels to predict Postoperative Vaginal Cuff Hematoma ; To evaluate tissue trauma and surgical inflammatory responses, venous peripheral blood samples (C-reactive protein) were taken on the first, second and seventh day postoperatively. CRP values were measured under standardized conditions using turbidometry. CRP levels (mg / dl) were recorded.

    Time frame: 1 week

  2. Relationship between CRP Levels and cuff hematoma; cuff hematoma measurement

    The patients were called to the outpatient clinic after the hysterectomy and evaluated by transvaginal ultrasonography (tvusg) for cuff hematoma.hematoma dimensions recorded in centimeters.

    Time frame: 15 days

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 18, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03879499
Responsible party
Pınar Kadirogulları (Principal investigator, Kanuni Sultan Suleyman Training and Research Hospital) — Principal investigator
First posted
Mar 18, 2019
Start date
Jan 1, 2017
Primary completion
Jan 1, 2018
Completion
Jan 1, 2018
Last update
Jul 18, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.

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