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WithdrawnNCT03869489Updated Sep 4, 2019

Decision Making in Video Games

An interventional study of Anodal left dorsolateral prefrontal cortex tDCS stimulation and Anodal right dorsolateral prefrontal cortex tDCS stimulation in Cognitive Change, sponsored by Tufts University. Withdrawn at 1 site in United States. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-09-04.

Sponsored by Tufts University · Not applicable, Interventional, and Basic science

Why this study was withdrawn
Funding Goals changed
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Non-randomized
Ages
18 Years to 35 Years
Sex
All
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Study summary

The purpose of this study is to determine whether anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal cortex induces approach motivation, and whether anodal tDCS applied to the right dorsolateral prefrontal cortex induces avoidance motivation. This study consists of three experiments: one in which an approach/avoidance video game is validated, one in which the effect of anger and fear on approach/avoidance is studied, and one in which the effect of tDCS is studied. Only the experiment in which the effect of tDCS is studied involves tDCS.

02

Conditions studied

  • Cognitive Change

Keywords

  • approach motivation
  • avoidance motivation
  • transcranial direct current stimulation
03

In context

Lead sponsor

Tufts University is the lead sponsor of 225 studies on the registry; 24 are open to participants now.

Of its 10 completed or terminated interventional studies of FDA-regulated products, 7 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Normal hearing and vision

Exclusion criteria

Exclusion Criteria:

  • Left-handedness
  • History of seizure, head injury (including neurosurgery), brain injury, diagnosis or a neurological or psychiatric disorder, metal in the head, sensitive scalp
  • History of anxiolytic and/or antidepressant medications
  • Participation in Experiment #1 or Experiment #2 of the larger study
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Non-randomized
Intervention model
Single group
Masking
Single (Participant)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    Anodal left dorsolateral prefrontal cortex tDCS stimulation

    Device: Anodal left dorsolateral prefrontal cortex tDCS stimulation

  • Experimental
    Anodal right dorsolateral prefrontal cortex tDCS stimulation

    Device: Anodal right dorsolateral prefrontal cortex tDCS stimulation

  • Sham comparator
    Sham tDCS stimulation

    Device: Sham tDCS stimulation

Interventions

  • DeviceAnodal left dorsolateral prefrontal cortex tDCS stimulation

    Anodal tDCS will be applied to the left dorsolateral prefrontal cortex of participants

  • DeviceAnodal right dorsolateral prefrontal cortex tDCS stimulation

    Anodal tDCS will be applied to the right dorsolateral prefrontal cortex of participants

  • DeviceSham tDCS stimulation

    Sham tDCS stimulation will be applied

06

What researchers measure

Primary outcomes

  1. Avoidance-Approach time difference

    Median of the difference between time to approach and time to avoid a stimulus

    Time frame: 1 year

07

Study locations

1 site
  • Center for Applied Brain and Cognitive Sciences
    Medford, Massachusetts 02155, United States
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References and documents

Individual participant data

Plan to share: No — N/A. Study withdrawn

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 4, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03869489
Lead sponsor
Tufts University
Responsible party
Sponsor
First posted
Mar 11, 2019
Start date
Nov 2019 (estimated)
Primary completion
Apr 2020 (estimated)
Completion
Apr 2020 (estimated)
Last update
Sep 4, 2019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.

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