CClinicalTrials.gg
CompletedNCT03868683GIFUpdated Jul 17, 2020

The Glycemic Effect of Added Sugar on Bake Beans

An interventional study of Glucose Reference 1 and Glucose Reference 2 in Diabetes Mellitus, Type 2, Obesity and PreDiabetes, sponsored by Singapore Institute of Food and Biotechnology Innovation. Completed at 1 site in Singapore. Open to male participants aged 21 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-07-17.

Sponsored by Singapore Institute of Food and Biotechnology Innovation · Not applicable, Interventional, and Other

From the registry’s dates

  • Registered 6 months after the study started (first participant enrolled Aug 2018, registered Mar 2019).
Phase
Not applicable
Study type
Interventional
Enrollment
12
Allocation
Randomized
Ages
21 Years to 60 Years
Sex
Male
01

Study summary

To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.

Read the detailed description

There will be a total of 7 test session. Each session will last for 3 hours. At each test session, volunteers will be served with 7 test meals and blood will be collected. After an overnight fast, subjects will visit the research center. Two fasting capillary blood samples will be collected via fingerpick. Following the fasting samples, volunteers will consume the test meals. Further blood samples will be collected at 15, 30, 45, 60, 90, 120, 150, 180 minutes after the ingestion of test meal. These samples will be used to analyses for whole capillary blood glucose. At every 30 minute interval, samples will be collected for analysis of capillary plasma insulin.

02

Conditions studied

  • Diabetes Mellitus, Type 2
  • Obesity
  • PreDiabetes
03

In context

Diabetes Mellitus, Type 2

9,359 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,318 are open to participants now.

This study's enrollment of 12 is below the median of 80 across 7,525 interventional studies indexed under Diabetes Mellitus, Type 2.

Browse Diabetes Mellitus, Type 2 studies →

Lead sponsor

Singapore Institute of Food and Biotechnology Innovation is the lead sponsor of 69 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years to 60 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • Chinese ethnicity
  • Age ≥21 and ≤ 60 years
  • Body mass index between 18.5 to 25 kg/m2
  • Normal blood pressure \<140/90 mmHg
  • Fasting blood glucose \<6.0 mmol/L
  • In general good health

Exclusion criteria

Exclusion Criteria:

  • Current Smoker
  • have any metabolic diseases (such as diabetes, hypertension etc)
  • have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
  • having medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)
  • have intolerances or allergies to any foods
  • partake in sports at the competitive and/or endurance levels
  • intentionally restrict food intake
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
12 participants (actual)

Study arms

  • Other
    Glucose Reference 1

    Glucose solution containing 30 g of glucose

    Other: Glucose Reference 1

  • Other
    Glucose Reference 2

    Glucose solution 2 containing 30 g of glucose

    Other: Glucose Reference 2

  • Other
    Glucose Reference 3

    Glucose solution 3 containing 30 g of glucose

    Other: Glucose reference 3

  • Experimental
    Sucrose

    Sucrose solution containing 30 g of sucrose

    Other: Sucrose

  • Experimental
    Regular Bake beans in tomato sauce

    Bake bean in tomato sauce with high levels of sucrose (37%)

    Other: Regular Bake beans in tomato sauce

  • Experimental
    Bake beans in tomato sauce, reduced sugar

    Bake bean in tomato sauce with medium levels of sucrose (29.9%)

    Other: Bake beans in tomato sauce, reduced sugar

  • Experimental
    Bake beans in tomato sauce, low GI

    Bake bean in tomato sauce with low levels of sucrose (18.5%)

    Other: Bake beans in tomato sauce, low GI

Interventions

  • OtherGlucose Reference 1

    30 g of glucose dissolved in 250 ml of water

  • OtherGlucose Reference 2

    30 g of glucose dissolved in 250 ml of water

  • OtherGlucose reference 3

    30 g of glucose dissolved in 250 ml of water

  • OtherSucrose

    30 g of Sucrose dissolved in 250 ml of water

  • OtherRegular Bake beans in tomato sauce

    Bake beans in tomato sauce containing 14 g of sugar

  • OtherBake beans in tomato sauce, reduced sugar

    Bake beans in tomato sauce containing 12.2 g of sugar

  • OtherBake beans in tomato sauce, low GI

    Bake beans in tomato sauce containing 7.2 g of sugar

06

What researchers measure

Primary outcomes

  1. Glucose [

    Whole capillary blood glucose will be measure using Hemocue analyser

    Time frame: Up to 180 minutes

Secondary outcomes

  1. Insulin

    Capillary plasma will be measure using Cobas analyser

    Time frame: Up to 180 minutes

07

Study locations

1 site
  • Clinical Nutrition Research Centre
    Singapore, 117599, Singapore
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 17, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03868683
Lead sponsor
Singapore Institute of Food and Biotechnology Innovation
Responsible party
JeyaKumar Henry (Principal Investigator, Singapore Institute of Food and Biotechnology Innovation) — Principal investigator
First posted
Mar 11, 2019
Start date
Aug 20, 2018
Primary completion
Apr 17, 2019
Completion
Apr 17, 2019
Last update
Jul 17, 2020

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.

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