CClinicalTrials.gg
Status unknownNCT03853980Updated Mar 6, 2020

The INFORM Study: Rotational Fractional Resection for Submental Contouring

An interventional study of Focal Contouring System in Skin Laxity, sponsored by Recros Medica, Inc.. Status unknown at 14 sites in United States. Open to participants aged 30 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-03-06.

Sponsored by Recros Medica, Inc. · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Mar 2020), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
21
Allocation
Not applicable
Ages
30 Years and older
Sex
All
01

Study summary

Efficacy and safety of Rotational Fractional Resection (skin resection) in patients with moderate to severe submental skin laxity.

Read the detailed description

This is a prospective, multi-center, single-arm (non-randomized), interventional cohort, non-significant risk (NSR) study designed to investigate the efficacy and safety of Rotational Fractional Resection (skin resection) in patients with moderate to severe submental skin laxity. The total duration of study participation for each subject is approximately up to 4 months for each subject from the screening visit to the exit visit. The follow-up period will be approximately 3 months after the procedure. Eligible subjects will complete a total of 11 study visits: screening, procedure, and follow-up visits at 1, 2-4, 7, 14, 21, 30, 45, 60, and 90 days post-procedure.

02

Conditions studied

  • Skin Laxity

Browse trials for

Keywords

  • submental
  • laxity
03

Who can participate

Ages eligible
30 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy male or female
  • At least 30 years old
  • Moderate to severe submental laxity
  • Agree to maintain weight (±5%) for the duration of the study

Exclusion criteria

Exclusion Criteria:

  • Greater than mild submental fat
  • Previous intervention to treat submental fat or skin laxity
  • Use of aspirin, ibuprofen, naproxen, or Vitamin E within 14 days of the procedure
  • Severe acne, cystic acne or acne scars on neck
  • Trauma of chin or neck area
  • Skin infection or rash on neck
  • Psoriasis, hyperpigmentation, eczema, rosacea or vitiligo
  • History of scarring
  • Body mass index (BMI) >30
  • Clinically significant bleeding disorder
  • Anemia, kidney disease, or liver disease
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
21 participants (actual)

Study arms

  • Experimental
    Rotational fractional resection (RFR)

    Single treatment of skin resection (removal of loose skin)

    Device: Focal Contouring System

Interventions

  • DeviceFocal Contouring System

    Single treatment of skin resection (removal of loose skin)

05

What researchers measure

Primary outcomes

  1. Improved Skin Laxity

    Comparison of the submentum before and after procedure using the Submental Skin Laxity scale (0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe)

    Time frame: Pre-treatment and 90 days after treatment

  2. Subject Satisfaction: Subject Satisfaction Questionnaire

    Comparison of Subject satisfaction of the procedure as assessed using the Subject Satisfaction Questionnaire

    Time frame: Pre-treatment and 90 days after treatment

06

Study locations

14 sites
  • Aesthetx
    Campbell, California 95008, United States
  • Clinical Testing of Beverly Hills
    Encino, California 91436, United States
  • Westside Aesthetics
    Los Angeles, California 90025, United States
  • ATS Clinical Research
    Santa Monica, California 90404, United States
  • Moradi MD
    Vista, California 92083, United States
  • AboutSkin Research
    Greenwood Village, Colorado 80111, United States
  • Washington Institute of Dermatologic Laser Surgery
    Washington, District of Columbia 20005, United States
  • DeNova Research
    Chicago, Illinois 60611, United States
  • Juva Skin and Laser Center
    New York, New York 10022, United States
  • Clinical Research Center of the Carolinas
    Charleston, South Carolina 29407, United States
  • Brian Biesman, MD
    Nashville, Tennessee 37203, United States
  • Bellaire Dermatology Associates
    Bellaire, Texas 77401, United States
  • Sundaram Dermatology, Cosmetic & Laser Surgery Center
    Fairfax, Virginia 22031, United States
  • Premier Clinical Research
    Spokane, Washington 99202, United States
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03853980
Lead sponsor
Recros Medica, Inc.
Responsible party
Sponsor
First posted
Feb 26, 2019
Start date
Mar 18, 2019
Primary completion
Oct 31, 2020 (estimated)
Completion
Oct 31, 2020 (estimated)
Last update
Mar 6, 2020

Study contacts

Robin McIntosh
study director · Recros Medica

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion