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CompletedNCT03844698Updated May 4, 2022

Association Between Cancer and Sarcoidosis

An observational study in Sarcoidosis and Cancer, sponsored by University of Miami. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-05-04.

Sponsored by University of Miami · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
171
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to develop a clinical dataset of sarcoidosis patients with a diagnosis of cancer who are categorized by date of birth, sex, race/ethnicity, clinical information, laboratory and imaging information, time of sarcoidosis onset, cancer type and treatment, time of cancer diagnosis, stage and grade.

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Conditions studied

  • Sarcoidosis
  • Cancer

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Keywords

  • sarcoidosis, cancer, paraneoplastic, treatment, outcome
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In context

Sarcoidosis

278 studies on the registry are indexed under Sarcoidosis; 57 are open to participants now.

This study's enrollment of 171 is above the median of 125 across 106 observational studies indexed under Sarcoidosis.

Browse Sarcoidosis studies →

Lead sponsor

University of Miami is the lead sponsor of 820 studies on the registry; 161 are open to participants now.

Of its 111 completed or terminated interventional studies of FDA-regulated products, 93 (84%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients with cancer who were seeking or receiving medical care at the University of Miami that satisfy the inclusion and exclusion criteria of study are eligible to participate.

Inclusion criteria

  • Clinical diagnosis of Sarcoidosis following cancer
  • Granulomatous reaction must be proven by pathology

Exclusion criteria

Exclusion Criteria:

. Aged younger than 18 years old.

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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
171 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Patients with Sarcoidosis and Cancer

    These group of patients have a diagnosis of Sarcoidosis and Cancer on the Pathological Report.

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What researchers measure

Primary outcomes

  1. Pathology Proven Sarcoidosis In Patients with Cancer

    Number of Participants With Sarcoidosis Events as Assessed by Positive Granulomatous Reaction in the Biopsies of Lung, Mediastinal Lymph Nodes, or Other Organs After Cancer Diagnosis.

    Time frame: up to 10 years

Secondary outcomes

  1. Cancer Cytogenetics and Sarcoidosis

    Number of Participants With Sarcoidosis Events as Assessed by Cancer Cytogenetic Profiles of Cancer.

    Time frame: up to 10 years

  2. Treatment Requirement of Sarcoidosis

    Number of Participants With Sarcoidosis Events as Assessed by Requirement of Treatment with Steroid or Other Anti-Sarcoid Medications in Patients with Cancer.

    Time frame: up to 10 years

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Study locations

1 site
  • University of Miami, Miller School of Medicine
    Miami, Florida 33136, United States
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References and documents

Publications

  • Murthi M, Yoshioka K, Cho JH, Arias S, Danna E, Zaw M, Holt G, Tatsumi K, Kawasaki T, Mirsaeidi M. Presence of concurrent sarcoid-like granulomas indicates better survival in cancer patients: a retrospective cohort study. ERJ Open Res. 2020 Oct 26;6(4):00061-2020. doi: 10.1183/23120541.00061-2020. eCollection 2020 Oct. PubMed 33263026 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 4, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03844698
Lead sponsor
University of Miami
Responsible party
Sponsor
First posted
Feb 18, 2019
Start date
Jul 4, 2019
Primary completion
Sep 16, 2021
Completion
Sep 16, 2021
Last update
May 4, 2022

Study contacts

Mehdi Mirsaeidi, MD
principal investigator · University of Miami

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.

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