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CompletedNCT03836469RELANCEUpdated Feb 20, 2024

Retrospective Epidemiological Study of Locally Advanced Non Small Cell Lung Cancer Patients in Brazil

An observational study in Lung Cancer, Non-small Cell, sponsored by Latin American Cooperative Oncology Group. Completed at 1 site in Brazil. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-02-20.

Sponsored by Latin American Cooperative Oncology Group · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
403
Ages
18 Years and older
Sex
All
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Study summary

RELANCE is a large multi-institutional study that aims to retrospectively collect information about diagnostic, treatment and outcome of patients diagnosed with locally advanced NSCLC in Brazil. It is hypothesized that there is a great heterogeneity in treatment patterns owing to inequities in access to adequate staging methods, optimal treatment and multidisciplinary teams in Brazil.

Read the detailed description

RELANCE study will collect sociodemographic and clinical data of patients diagnosed with locally advanced NSCLC in the period of January 2015 and Jun 2019 in the participating institutions. Socio-demographic characteristics, clinicopathological features, treatments patterns and outcomes will be recovered from medical charts. Disease status and survival data will be collected up to the last date of follow-up June 2021.

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Conditions studied

  • Lung Cancer, Non-small Cell

Keywords

  • Lung cancer
  • Non-small cell
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In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's enrollment of 403 is above the median of 189 across 1,514 observational studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Latin American Cooperative Oncology Group is the lead sponsor of 46 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients diagnosed with stage IIIA or IIIB NSCLC in the period of January 2015 to December 2016.

Inclusion criteria

  1. Patients aged 18 years or older;
  2. Histologically or cytological diagnosis of NSCLC in the period of January 2015 to December 2016;
  3. Locally Advanced NSCLC defined as clinical stage IIIA and IIIB according to 7th Edition TNM Staging System;
  4. Any NSCLC histological subtype and molecular mutation;
  5. Any Eastern Cooperative Oncology Group (ECOG) Performance Status (0 to 4) at diagnosis;
  6. Patients assigned by treating physician to any therapy or palliative care;
  7. Access to patient medical chart for data collection.

Exclusion criteria

Exclusion Criteria:

  1. Small cell lung cancer and non-invasive NSCLC;
  2. Synchronic NSCLC or second primary tumour in the last 5 years (except non-melanoma skin cancer).
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
403 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Overall survival

    defined as time from diagnosis to death of any cause;

    Time frame: Up to June 30, 2018

Secondary outcomes

  1. Progression free survival

    defined as time from any line of treatment to progression of the disease or death of any cause

    Time frame: Up to June 30, 2018

  2. Time to next treatment

    defined as time from start of the any treatment to the beginning of a second therapy

    Time frame: Up to June 30, 2018

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Study locations

1 site
  • AC Camargo
    São Paulo, SP, Brazil
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 20, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03836469
Lead sponsor
Latin American Cooperative Oncology Group
Collaborators
AstraZeneca
Responsible party
Sponsor
First posted
Feb 11, 2019
Start date
Sep 25, 2019
Primary completion
Jun 9, 2022
Completion
Jun 9, 2022
Last update
Feb 20, 2024

Study contacts

Vladmir Cláudio Cordeiro de Lima
principal investigator · Latin American Cooperative Oncology Group

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.

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