An observational study in Ankle Dislocation and Chronic Ankle Instability, sponsored by University Hospital, Lille. Terminated at 1 site in France. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-31.
Sponsored by University Hospital, Lille · Observational
Chronic ankle instability is a common condition in the active adult population and characterized by the occurrence of repeated giving way and/or recurrent ankle sprains. Multiple underlying deficits have been proposed, among which ankle muscle strength deficits, proprioception deficits, ( static and dynamic balance disorders, and articular laxity. Unfortunately, no consensus exists on which clinical tests should be realized to determine if one of these underlying deficits is predominant and as a result could guide the rehabilitation process. The study hypothesis is that people with chronic ankle instability might be heterogenous and could be divided in different subgroups as a function of underlying deficits. Therefore, this study aims to evaluate the capacity of different clinical tests to differentiate people with chronic ankle instability from healthy people as well as between each other.
University Hospital, Lille is the lead sponsor of 625 studies on the registry; 141 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adults (18-45 yrs) living in the northern part of France close to or in Lille, Saint-Omer and Amiens
Exclusion Criteria:
Male or female subjects aged 18-45, presenting : * at least one acute lateral ankle sprain (i.e. initial ankle sprain more than 12 months before inclusion), * at least one residual symptom (giving way OR sensation of instability OR recurrent ankle sprain), confirmed by a score \< 24 on the Chronic Ankle Instability Tool (CAIT) * Impact on activities of daily living and sport, score \< 90% on Foot and Ankle Ability Measure (FAAM) and \< 80% on FAAM-sport Case subjects are free of any other lower extremity pathologies or pain Subjects presenting bilateral chronic ankle instability are excluded
Male or female subjects aged 18-45 (matched with case Healthy subjects), without any lower extremity pathologies
Static balance tests
Static balance tests ( DLS and SLS (both ankles tested) ; Stabilometry) are composite measure * Centre of Pressure (COP) displacement (mm) ; * COP velocity (mm/s) * COP area (mm²) * COP time-to-boundary (TTB) (s) * Number of foot lifts (integer)
Time frame: Baseline
the Star Excursion Balance Test (SEBT)
Dynamic balance test : SEBT (both ankles tested) : are composite measure * Distance reached in anterior direction (% leg length) * Distance reached in posteromedial direction (% leg length) * Distance reached in posterolateral direction (% leg length) * Time used to reach (s) * COP displacement (mm) * COP velocity (s) * COP area (mm²) * COP time-to-boundary (TTB) (s)
Time frame: Baseline
Hop tests
Hop tests (both ankles tested) : SLHD et SH ; are composite measure * Distance reached (m) * Max inversion angle ankle joint (°) * Max internal rotation angle ankle joint (°) * Max vertical Ground Reaction Force (GRF) at landing (N) * Max lateral GRF (N) * Time used to complete 10 hops (s)
Time frame: Baseline
Strength tests (both ankles tested)
Isokinetic strength tests (both ankles tested) : * Plantar flexor peak torque (Nm) * Dorsiflexor peak torque (Nm) * Inversion peak torque (Nm) * Eversion Peak torque (Nm)
Time frame: Baseline
Intra-class correlation coefficients (reproducibility test-retest)
Intra-class correlation coefficients (reproducibility test-retest) calculated on the subset of the parameters identified by the main analysis. Recyclability of the functional clinical tests : Normality testing /Sample comparison
Time frame: Baseline and 1-4 weeks after baseline
This study is terminated, as verified in May 2022. You cannot join it, but the record below documents what was studied.
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University Hospital, Lille