An interventional study of Hypertonic saline in Intestinal Obstruction Fluid Management With Hypertonic Saline, sponsored by Cairo University. Status unknown at 1 site in Egypt. Open to participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-11-14.
Sponsored by Cairo University · Not applicable, Interventional, and Supportive care
Background and Rationale :
Perioperative fluid management is a challenging issue in surgical care especially in a procedure specific model. Recently hypertonic saline (HS) has the advantage of using the patient's own total body water by drawing interstitial space. Although it still controversial whether HS is associated with benefits in specific patient populations, particularly with respect to site of lesion and illness severity; these data provide insight into therapeutic modalities to curtail ileus formation.
Objectives :
Study population \& Sample size :
There were no previous trials comparing the two studied groups of the current trial. We expected a small standardized effect size of 0.2. Based on this effect size, 25 subjects will be needed to elicit the difference between the two groups at an alpha level of 0.05 and power of 0.9 (Whitehead et al; 2016).
160 studies on the registry are indexed under Intestinal Obstruction; 27 are open to participants now.
This study's planned enrollment of 50 is below the median of 80 across 80 interventional studies indexed under Intestinal Obstruction.
Browse Intestinal Obstruction studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Received Hypertonic saline 3% as resuscitation fluid.
Drug: Hypertonic saline
Received Hypertonic saline 1.8% as resuscitation
Drug: Hypertonic saline
resuscitation fluid
Total volume of infused fluids
the total volume of fluids given to subjects intraoperatively and postoperatively
Time frame: 24 hours
surgical complications rate
the rate of surgical complications i.e leakage and wound dehisence
Time frame: 4 days
Plan to share: Yes
No publications or documents are linked to this record.
This study is status unknown, as verified in Nov 2018. You cannot join it, but the record below documents what was studied.
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Cairo University