An observational study in Severe Eosinophilic Asthma, sponsored by Sotiria General Hospital. Status unknown at 1 site in Greece. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-11-13.
Sponsored by Sotiria General Hospital · Observational
Daily physical activity in adult patients with asthma remains overlooked. Limited evidence demonstrates reduced levels of daily physical activity in asthma populations but studies examining the potential effect of available therapies are missing. This study aims to investigate the overall levels of daily physical activity in patients with severe eosinophilic asthma and whether anti-interleukin-5 therapy with mepolizumab, on top of existing, maximal, and optimised asthma treatment, may improve patient's daily physical activity.
A multi-centre, prospective, observational study of continuous patients who fulfil the definition of severe asthma and the criteria for mepolizumab (nucala; GSK) therapy. Patients have their daily physical activity recorded using triaxial accelerometry (DynaPort MoveMonitor; McRoberts) prior to treatment, and at 6 and 12 months of mepolizumab therapy (100 mg subcutaneously once every 4 weeks).
3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.
This study's planned enrollment of 50 is below the median of 150 across 970 observational studies indexed under Asthma.
Browse Asthma studies →This is the only study on the registry with Sotiria General Hospital as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Adult patients with severe asthma, already on maximal and optimised treatment who fulfil the criteria for mepolizumab add-on therapy.
Inclusion Criteria:
Exclusion Criteria: Comorbidities limiting physical activity
100 milligrams subcutaneously once every 4 weeks
Change in daily moving time
Moving time in minutes
Time frame: 7 days
Change in daily movement intensity
Movement intensity in m/s\^2
Time frame: 7 days
Change in daily time in moderate-to-vigorous-intensity activity
Time in moderate-to-vigorous-intensity activity in minutes
Time frame: 7 days
Change in daily steps
Step count
Time frame: 7 days
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Nov 2018. You cannot join it, but the record below documents what was studied.
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