A Phase 2 interventional study of 5% fluorocalcium phosphosilicate dentifrice and 5% potassium nitrate dentifrice in Dentinal Hypersensitivity, sponsored by Government Dental College and Research Institute, Bangalore. Completed at 1 site in India. Open to participants aged 25 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-11-13.
Sponsored by Government Dental College and Research Institute, Bangalore · Phase 2, Interventional, and Treatment
Aim of this study was to assess and compare the efficacy of a dentifrice containing 5% fluoro calcium phosphosilicate and dentifrice containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo over a period of 6 weeks.
A total of 120 subjects were divided into 3 groups randomly. Group 1 was given the dentifrice containing 5% fluoro calcium phosphosilicate ,Group 2 was given the dentifrice containing potassium nitrate and group 3 was given placebo. Sensitivity scores (VAS score) were recorded at baseline, 2 weeks, 6 weeks.
Government Dental College and Research Institute, Bangalore is the lead sponsor of 38 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
dentifrice containing 5% fluorocalcium phospho silicate prescribed and VAS score assessed at Baseline, 2 weeks, 6 weeks.
Other: 5% fluorocalcium phosphosilicate dentifrice
dentifrice containing 5% potassium nitrate prescribed and VAS score assessed at Baseline, 2weeks, 6 weeks .
Other: 5% potassium nitrate dentifrice
dentifrice without the active ingredient prescribed and VAS score assessed at Baseline, 2weeks, 6 weeks .
Other: Placebo dentrifice
dentifrice containing 5% fluorocalcium phosphosilicate and VAS score assessed at Baseline, 2 weeks, 6 weeks
5% potassium nitrate dentifrice and VAS score assessed at Baseline, 2weeks, 6 weeks.
placebo dentifrice and VAS score assessed at Baseline, 2weeks, 6 weeks
Visual Analogue Scale score for Dentinal Hypersensitivity
Based on a 10-cm VAS score which was used to measure tooth sensitivity, a pain-free response was allotted a score of zero whereas a score of 10 was given to subjects with excruciating pain or discomfort.
Time frame: Change in VAS score from Baseline to 12 weeks
This study is completed, as verified in Nov 2018. You cannot join it, but the record below documents what was studied.
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Government Dental College and Research Institute, Bangalore