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Status unknownNCT03700489Updated Oct 9, 2018

Mycological Comparative Study on Maxillary Dentures of Two Different Materials

An interventional study of titanium dioxide denture in Effect of Tio2 Nanoparticles on Candida Aggregation, sponsored by Ali ibrahim mahmoud shamardal. Status unknown. Open to participants aged 30 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-10-09.

Sponsored by Ali ibrahim mahmoud shamardal · Not applicable, Interventional, and Prevention

The sponsor has not verified this record recently (last verified Oct 2018), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
34
Allocation
Randomized
Ages
30 Years to 55 Years
Sex
All
01

Study summary

Cross over design the investigator divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified by titanium dioxide nanoparticles and after washout period alternatively group (a) will receive the acrylic denture modified by titanium dioxide nanoparticles AND group (b) will receive rapid heat cured denture base material the investigator will take swaps from dentures to count the candida species

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Conditions studied

  • Effect of Tio2 Nanoparticles on Candida Aggregation
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In context

Lead sponsor

This is the only study on the registry with Ali ibrahim mahmoud shamardal as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Completely edentulous maxillary arch and partially dentate mandibular arch with adequate interarch space.
  • The edentulous ridges should be covered by firm healthy mucosa.
  • Angle class I maxillomandibular relation.
  • Healthy and cooperative patient

Exclusion criteria

Exclusion Criteria:

  • Patients with bad habits as severe clenching or bruxism, drug or alcohol addiction, moderate or heavy smoking (greater than 10 cigarettes per day).
  • Previous history of radiotherapy or chemotherapy.
  • Any skeletal problem dictates surgical intervention
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
34 participants (estimated)

Study arms

  • Experimental
    patients take titanium dioxide denture

    patients will receive titanium dioxide denture (made from conventional acrylic resin modified by titanium dioxide nanoparticles ) for 1 month in the initial phase of the trial then in the later phase after one month they will receive( rapid heat cured acrylic resin)denture

    Other: titanium dioxide denture

  • Placebo comparator
    patients take rapid heat denture

    patients will receive rapid heat denture for 1 month in the initial phase of the trial then in the later phase patients will receive titanium dioxide denture (made from conventional acrylic resin modified by titanium dioxide nanoparticles )

    Other: titanium dioxide denture

Interventions

  • Othertitanium dioxide denture

    patients will receive titanium dioxide denture (made from acrylic resin with titanium dioxide nanoparticles ) for 1 month in the initial phase then in the second phase after one month they will receive( rapid heat cured acrylic resin)denture according to the principle of crossover des

06

What researchers measure

Primary outcomes

  1. Mycological investigation

    Count of candida on the fitting surface of denture by (CFU) unit

    Time frame: 6 months

07

Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 9, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03700489
Lead sponsor
Ali ibrahim mahmoud shamardal
Responsible party
Ali ibrahim mahmoud shamardal (Principal Investigator, Cairo University) — Sponsor-investigator
First posted
Oct 9, 2018
Start date
Oct 20, 2018 (estimated)
Primary completion
May 1, 2019 (estimated)
Completion
Jun 1, 2019 (estimated)
Last update
Oct 9, 2018

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2018. You cannot join it, but the record below documents what was studied.

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