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Active, not recruitingNCT03665948Updated May 16, 2024

Effect of Ketogenic and Carbohydrate Diet in Crossfit

An interventional study of Dietary Intervention - Ketogenic Diet (KD) and Dietary Intervention - Low-Glycemic Index Diet (CHO-LGI) in Nutrition, Ketogenic Dieting and Low Glycemic Index Diet, sponsored by Poznan University of Physical Education. Active, not recruiting at 1 site in Poland. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-05-16.

Sponsored by Poznan University of Physical Education · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Nov 2024, 1 year 11 months ago, but the record still lists the study as active, not recruiting.
  • Registered 1 year 7 months after the study started (first participant enrolled Jan 2017, registered Sep 2018).
Phase
Not applicable
Study type
Interventional
Enrollment
70
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
All
01

Study summary

The purpose of the presented study was to assess the influence of Ketogenic (KD) and a carbohydrate diet with a low glycemic index (CHO-LGI) of a 4-week diet on physical and specific performance capacity, exercise metabolism, as well as concentrations of the selected biochemical blood markers in Crossfit- trained athletes, in a randomised and parallel trial.

Read the detailed description

The impact of various dietary strategies, including the alternative ketogenic diet - recently popular among strength athletes, has not been unequivocally assessed in the high-intensity sport disciplines that Crossfit belongs to. There is also a lack of data in these disciplines about the potential longer adaptation of athletes to the very low carbohydrate intake resulting from the ketogenic diet and its impact in high-intensity Crossfit training. Therefore, the purpose of this study was the assessment of the influence of a 4-week KD and a CHO-LGI diet on physical and specific performance capacity, exercise metabolism, as well as concentrations of the selected biochemical blood markers in Crossfit- trained athletes, in a randomised and parallel trial.

02

Conditions studied

  • Nutrition
  • Ketogenic Dieting
  • Low Glycemic Index Diet
  • Sport
  • Crossfit

Keywords

  • Sports Nutrition
  • Ketogenic Diet
  • Low Glycemic Index Diet
  • Crossfit
  • Physical capacity
  • Performance
  • Exercise metabolism
  • Training support
03

In context

Lead sponsor

Poznan University of Physical Education is the lead sponsor of 90 studies on the registry; 27 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • written consent to participate,
  • a current medical clearance to practice sports,
  • training experience: at least 2 years,
  • minimum of 4 workout sessions (Crossfit) a week.

Exclusion criteria

Exclusion Criteria:

  • current injury,
  • any health-related contraindication,
  • declared general feeling of being unwell,
  • unwilling to follow the study protocol,
  • smoking, illicit drug use, alcohol consumption greater than 1-2 drinks/week, dietary supplements use less than 3 weeks before the study,
  • females- being pregnant or planning to become pregnant during the study.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
70 participants (estimated)

Study arms

  • Experimental
    Ketogenic Diet (KD)

    Group consuming very low carbohydrate ketogenic diet. The ketogenic diet model was energetically normalized (covered the estimated energy expenditure) and assumed coverage of the daily energy requirement up to 5% of energy from carbohydrates. Proteins were administered in the amount of 1.7 g per kilogram of body mass. The remaining energy needs were covered with fats (fats covered more than 75% of the daily energy requirement). Each of the subjects in this group received 10-day menus.

    Other: Dietary Intervention - Ketogenic Diet (KD)

  • Active comparator
    Low-Glycemic Index Diet (CHO-LGI)

    Group consuming carbohydrate, low-glycemic index diet. The carbohydrate diet model with a low glycemic index was energetically normalized (covered the estimated energy expenditure) and assumed coverage of the daily energy requirement of 25% of fat. Proteins were administered in the amount of 1.7 g per kilogram of body mass. The remaining energy needs were covered with carbohydrates (carbohydrates covered about \~55% of the daily energy requirement). The glycemic index of individual meals as well as the daily diet was calculated in accordance with the appropriate recommendations. Each of the subjects in this group received 10-day menus.

    Other: Dietary Intervention - Low-Glycemic Index Diet (CHO-LGI)

Interventions

  • OtherDietary Intervention - Ketogenic Diet (KD)

    The experimental procedure for each randomly assigned participant included a 4-week of KD diet.

  • OtherDietary Intervention - Low-Glycemic Index Diet (CHO-LGI)

    The experimental procedure for each randomly assigned participant included a 4-week of CHO-LGI diet.

06

What researchers measure

Primary outcomes

  1. Changes in aerobic capacity following dietary intervention

    Time frame: Baseline and after 4 weeks

  2. Changes in CrossFit-specific performance capacity (Fight Gone Bad test) following dietary intervention

    The number of correctly performed repetitions of exercises (reps)

    Time frame: Baseline and after 4 weeks

  3. Changes in energy substrates utilization following dietary intervention

    Fats (g/min) and carbohydrates (g/min) oxidation analysis

    Time frame: Baseline and after 4 weeks

Secondary outcomes

  1. Changes in fat mass and fat free mass following dietary intervention

    Fat mass (kg) and fat free mass (kg) analysis

    Time frame: Baseline and after 4 weeks

  2. Changes of red and white blood cell concentration in blood following dietary intervention

    Red blood cells (RBC) \[mln/mm³\] and white blood cells (WBC) \[mln/mm³\] concentration analysis

    Time frame: Baseline and after 4 weeks

  3. Changes in blood glucose and hemoglobin concentration following dietary intervention

    Hemoglobin (Hb) \[g/dl\] and glucose \[g/dl\] concentration analysis

    Time frame: Baseline and after 4 weeks

  4. Changes in blood hematocrit levels following dietary intervention

    Hematocrit (HCT) \[%\] level analysis

    Time frame: Baseline and after 4 weeks

  5. Changes of testosterone, cortisol, urea, lactate and pyruvate concentration in blood following dietary intervention

    Testosterone \[mmol/L\], cortisol \[mmol/L\], urea \[mmol/L\], lactate \[mmol/L\] and pyruvate \[mmol/L\] concentration analysis

    Time frame: Baseline and after 4 weeks

  6. Changes of creatine kinase, lactate dehydrogenase, alanine aminotransferase and aspartate aminotransferase activity in blood after following dietary intervention

    Creatine kinase \[U/L\], lactate dehydrogenase \[U/L\], alanine aminotransferase \[U/L\] and aspartate aminotransferase \[U/L\] activity analysis

    Time frame: Baseline and after 4 weeks

07

Study locations

1 site
  • Institute of Human Nutrition and Dietetics, Poznan University of Life Sciences
    Poznań, 60-624, Poland
08

References and documents

Publications

  • Durkalec-Michalski K, Nowaczyk PM, Siedzik K. Effect of a four-week ketogenic diet on exercise metabolism in CrossFit-trained athletes. J Int Soc Sports Nutr. 2019 Apr 5;16(1):16. doi: 10.1186/s12970-019-0284-9. PubMed 30953522 ↗

Individual participant data

Plan to share: Undecided — Shared data will be exclusively related to the level recorded indicators (anaerobic capacity and specific performance capacity indicators, exercise metabolism, levels of biochemical markers, and body composition), without personal data. The data obtained will be attached to scientific publications, depending on the requirements of the journal.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 16, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03665948
Lead sponsor
Poznan University of Physical Education
Collaborators
Poznan University of PhysED, Poznan University of Life Sciences
Responsible party
Krzysztof Durkalec-Michalski (Associate Professor, Poznan University of Physical Education) — Principal investigator
First posted
Sep 11, 2018
Start date
Jan 9, 2017
Primary completion
Nov 1, 2024 (estimated)
Completion
Dec 20, 2024 (estimated)
Last update
May 16, 2024

Study contacts

Jan Jeszka, Professor
study chair · Institute of Human Nutrition and Dietetics, Poznan University of Life Sciences

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2024. You cannot join it, but the record below documents what was studied.

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