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CompletedNCT03665324FA2VUpdated Sep 11, 2018

Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.

An observational study in Supraventricular Arrhythmias, sponsored by Rennes University Hospital. Completed at 1 site in France. Open to participants aged 35 Years and older. Per ClinicalTrials.gov, last updated 2018-09-11.

Sponsored by Rennes University Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
100
Ages
35 Years and older
Sex
All
01

Study summary

Supraventricular arrhythmias (including atrial fibrillation) are the most common arrhythmias of the veteran athlete and have a major impact in terms of morbidity and mortality. Although moderate sports practice has been shown to decrease the occurrence of these arrhythmias, it has also been shown that very intense athletic activity is associated with an increased risk of developing atrial fibrillation. The pathophysiological mechanism is not clearly understood. However, it has already been shown that intensive sports practice leads to electrical and morphological atrial remodeling, which could be the cause of the occurrence of supraventricular arrhythmias for these athletes.

For sedentary patients, two major tools predict the risk of the onset of supraventricular arrhythmia: the electrocardiogram (ECG) and transthoracic echocardiography (ETT), particularly with the study of atrial function by the analysis of myocardial deformities.

Read the detailed description

No studies have tested these two tools for the evaluation of atrial remodeling of the veteran athlete to predict which ones are at risk of developing supraventricular arrhythmias.

However, the identification of predictive factors would make it possible to identify at-risk athletes and thus provide them with adapted sporting practice advice and personalized follow-up.

The aim of the study is to evaluate the relationship between atrial remodeling assessed by ECG and ETT with the occurrence of supraventricular arrhythmia by comparing an athlete group with supraventricular arrhythmia with a control group of healthy athletes.

02

Conditions studied

  • Supraventricular Arrhythmias

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Keywords

  • Supraventricular arrhythmias
  • veteran athlete
  • ECG
  • ETT
03

In context

Arrhythmias, Cardiac

885 studies on the registry are indexed under Arrhythmias, Cardiac; 235 are open to participants now.

This study's enrollment of 100 is below the median of 200 across 414 observational studies indexed under Arrhythmias, Cardiac.

Browse Arrhythmias, Cardiac studies →

Lead sponsor

Rennes University Hospital is the lead sponsor of 440 studies on the registry; 51 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Veteran athletes who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017

Inclusion criteria

  • Supraventricular arrhythmia group : Veteran athletes with documented paroxysmal supraventricular arrhythmias.
  • Control Group : Veteran athletes without documented supraventricular arrhythmia.

Exclusion criteria

Exclusion Criteria:

  • Any cardiopathy (valvulopathy, coronary heart disease, etc.).
  • Minor patients,
  • Major patients subject to legal protection (legal safeguards, guardianship)
  • Persons deprived of their liberty
  • Patients opposed to the use of their personal data.
05

Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
100 participants (actual)
Patient registry
No

Groups and cohorts

  • Veteran athletes with Supraventricular arrhythmias

    Subjects who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017 Veteran athletes (age\> 35 years) with documented paroxysmal supraventricular arrhythmias.

    Other: Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

  • Veteran athletes without supraventricular arrhythmia

    Subjects who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017 Veteran athletes (age\> 35 years) without documented supraventricular arrhythmia.

    Other: Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

Interventions

  • OtherEvaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

    Subjects will be retrospectively retrieved from the Sport Medicine Service of Rennes University Hospital database. Medical data will then be collected from the athletes' medical records. The ECG present in the medical file will be reinterpreted to obtain the resting heart rate, the amplitude of the P wave, the morphology of the P wave and the duration of the PR space. The data from the stress test will be found from reports in the medical records: resting heart rate, maximum heart rate, sustained peak load, arrhythmia during the test. ETTs will be retrieved from the local server. They will be reinterpreted to collect anatomical and functional cardiac data necessary for the study.

06

What researchers measure

Primary outcomes

  1. Study of atrial function by analysis of myocardial strain.

    Myocardial strain in extracted from ETT and compared between the two groups.

    Time frame: At the inclusion day

07

Study locations

1 site
  • Rennes University Hospital
    Rennes, 35000, France
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 11, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03665324
Lead sponsor
Rennes University Hospital
Responsible party
Sponsor
First posted
Sep 11, 2018
Start date
Apr 28, 2017
Primary completion
May 15, 2017
Completion
May 15, 2017
Last update
Sep 11, 2018

Study contacts

frederic SCHNELL, MD
principal investigator · Rennes University Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.

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