An observational study in Sports Accident and Athletes Heart, sponsored by Agne Slapsinskaite. Completed. Open to participants aged 16 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-09-05.
Sponsored by Agne Slapsinskaite · Observational
Recent developments in football have seen the sudden death of young football player due to aortic rupture hence reinforcing the controversy of football as a field with substantial risk for sudden cardiac arrest and death. Moreover, there is an argument that aortic dilatation and the subsequent event of thoracic aortic aneurysm may be an occupational disease due to the nature of some vocations (i.e., military and security personnel, blue collar workers, weightlifters, athletes etc.). Of particular importance, there is some evidence that elite athletic training is associated with small but significantly larger aortic root diameter. The purpose of this study was to investigate aortic root adaptation to physical workload and to determine if aortic root's and left ventricle sizes are contingent upon the physical workload
A preliminary data was collected from a total of 944 subjects in Kaunas Sports Medicine Centre during the recruiting period in 2014-2015. Final data analysis consisted of 151 Caucasian subjects who met the inclusion criteria.
All subjects underwent two-dimensional (2D) transthoracic echocardiography (TTE) procedure. Prior to performing 2D TTE, subjects' arterial blood pressure, heart rate, height, weight, and self-reported physical activity levels were measured.
The Ultrasound system CX50 (Philips Ultrasound, Philips Healthcare, Philips Medical Systems Nederland, USA) - with transducer S5-1 was used in this study. Two physicians performed 2D TTE and averages for all variables of interest were computed. The measurements of aortic root and the left ventricle were drawn upon the guidelines of the American Society of Echocardiography and the European Association of Cardiovascular Imaging.
The maximal diameter of the sinuses of Valsalva was measured at end-diastole, in a strictly perpendicular plane to that of the long axis of the aorta using the edge to leading edge (L-L) convention. The aortic annulus was measured at midsystole from inner edge to inner edge (I-I). This was done in order to obtain the rounder shape and bigger diameter of aortic annulus.
This is the only study on the registry with Agne Slapsinskaite as lead sponsor.
Counted across the registry records on this site, refreshed daily.
The subjects were divided into groups according to gender (i.e., female, male), physical activity (i.e., athletes, non-athletes) and physical activity type (i.e., strength and endurance sports). Of the 151 subjects, 122 were athletes (41 females and 81 males) and 29 were non-athletes (14 females and 15 males). Of the 41 female athletes, 32 were endurance athletes, and 9 strength athletes. From 81 male athletes, 56 were endurance athletes, and 25 were strength athletes.
Exclusion Criteria:
122 were athletes (41 females and 81 males). Of the 41 female athletes, 32 were endurance athletes, and 9 strength athletes. From 81 male athletes, 56 were endurance athletes, and 25 were strength athletes.
Other: Physical load
29 were non-athletes (14 females and 15 males)
The impact of training on cardiac structure and function depends on the type, intensity and duration of the activity, as well as previous physical activity engagement, genetics and gender type. More knowledge about cardiac pathophysiologic training adaptation is needed.
Measurement of aortic root at aortic valve annulus (AA)
Changes in aortic root at aortic valve annulus (AA) and at individuals.
Time frame: Long-term adaptation more when 4 years of physical activity with 4.5 hours per week training sessions
Measurement of aortic root at sinus of Valsalva (VS)
Changes in aortic root at sinus of Valsalva (VS) individuals.
Time frame: Long-term adaptation more when 4 years of physical activity with 4.5 hours per week training sessions
Measurement of values of the left ventricle (LV): LV end-diastolic diameter (LVEDD)
Changes values of the left ventricle (LV): LV end-diastolic diameter (LVEDD)
Time frame: Long-term adaptation more when 4 years of physical activity with 4.5 hours per week training sessions
Measurement of values of interventricular septum thickness in diastole (IVSTd)
Changes values of interventricular septum thickness in diastole (IVSTd)
Time frame: Long-term adaptation more when 4 years of physical activity with 4.5 hours per week training sessions
LV posterior wall thickness in diastole (LVPWTd)
Changes values of LV posterior wall thickness in diastole (LVPWTd)
Time frame: Long-term adaptation more when 4 years of physical activity with 4.5 hours per week training sessions
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.
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