An interventional study of Cognitive bias modification training and Control training in Child Abuse, Child Neglect and Victimization, sponsored by Institute of Psychiatry, London. Completed at 2 sites in 2 countries. Open to participants aged 12 Years to 18 Years. Per ClinicalTrials.gov, last updated 2020-08-11.
Sponsored by Institute of Psychiatry, London · Not applicable, Interventional, and Basic science
Adolescents who have experienced adversity (childhood maltreatment and other forms of broader victimisation experiences) will be randomly allocated to receive a 5-session cognitive bias modification training (with attention and interpretation bias modification modules) or a control condition. Outcome measures include measures of cognitive biases and symptoms of psychopathology; in addition, in a subset of adolescents, brain activity data will be acquired. All adolescents will complete a feedback form, upon which acceptability of the intervention will be assessed.
Up to 80 adolescents aged 12-18 years who have experienced adversity (childhood maltreatment and other forms of broader victimisation experiences) from India and Nepal will be randomly allocated to receive a 5-session cognitive bias modification training (with attention and interpretation bias modification modules) or a control condition over a 2-week period.
Pre and post-assessment measures include measures of attention and interpretation biases and symptoms of internalising and externalising psychopathology. In addition, in a subset of adolescents, brain activity data acquired using EEG will be acquired either during resting or viewing emotional face stimuli. Data from these measures will be used to generate effect sizes of changes for each group as well as being used in a limited number of significance-testing analysis. All adolescents will complete a feedback form, upon which acceptability of the intervention will be assessed.
Institute of Psychiatry, London is the lead sponsor of 9 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
Participants will receive 5 training sessions, each session including attention bias modification and interpretation bias modification training modules
Behavioral: Cognitive bias modification training
Participants will receive 5 sessions that involve exercises that are matched to the task demands of the attention bias modification and interpretation bias modification training modules
Behavioral: Control training
These training sessions aim to modify a selective attention bias towards threat and a tendency to interpret ambiguous situations in threatening ways
These exercises are matched to the task demands of the modules of cognitive bias modification training
Attention biases for threatening stimuli
The investigators will use an experimental measure (a visual search task) that uses reaction times (RTs) to different experimental conditions to index the degree to which attention is captured by a threatening over a non-threatening stimulus.
Time frame: Immediately after the intervention (post-intervention)
Interpretation biases for threatening explanations
The investigators will use an experimental measure (an ambiguous scenarios task) that uses ratings to different experimental trials to index the degree to which individuals endorse threatening over benign interpretations
Time frame: Immediately after the intervention (post-intervention)
Symptoms of emotional, behavioural and social problems
5 subscales of the Strength and Difficulties questionnaire
Time frame: Immediately after the intervention (post-intervention)
Acceptability of intervention
The investigators have developed a 19-item self-report feedback, comprising quantitative ratings and qualitative responses. Across eleven items, young people rate on a 4-point Likert scale whether they found the training useful, satisfying, engaging, realistic, whether it impacted anxiety, mood, coping strategies, and other difficulties , and whether they would feel motivated to complete the sessions, including without a researcher present. Higher scores reflect greater endorsement. Each of these items will be reported separately rather than used to create composite scores. There are also 8 open ended questions for young people to leave their feedback on aspects they found helpful, unhelpful, liked, disliked, improvements they would want, and other general comments.
Time frame: Immediately after the intervention (post-intervention)
Event related potentials to emotional face presentations during Electroencephalogram (EEG) experiment
P1, N1, P2, N2, P3 event-related potentials during face presentation
Time frame: Immediately after the intervention (post-intervention)
Plan to share: Yes — All data will be anonymised such that each participant will be associated with a unique identification (ID) number. These will be uploaded to data repository sites once data collection, analysis and dissemination is completed
Supporting information: Study protocol, Sap, Icf, Csr, Analytic code
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2020. You cannot join it, but the record below documents what was studied.
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Institute of Psychiatry, London