An observational study in Obesity, Morbid, sponsored by Norwegian University of Science and Technology. Recruiting at 1 site in Norway. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-08-13.
Sponsored by Norwegian University of Science and Technology · Observational
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on paracetamol are investigated.
Patients referred for bariatric surgery (gastric bypass or sleeve gastrectomy)
Exclusion Criteria:
Patients are tested for their normal prescription paracetamol medication
Also known as: Acetaminophen, Acephen, Tylenol
Paracetamol concentration in blood serum (area under curve (AUC))
Time frame: From baseline to 1 year postoperatively
Plan to share: Undecided
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Norwegian University of Science and Technology