An interventional study of rTMS in Attention Deficit Hyperactivity Disorder, sponsored by Hangzhou Normal University. Completed at 1 site in China. Open to participants aged 19 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-08-07.
Sponsored by Hangzhou Normal University · Not applicable, Interventional, and Treatment
Attention deficit hyperactivity disorder (ADHD) patients have some problem with sustained attention. The dorsal anterior cingulate cortex (dACC) plays a key role for attention control. It has been found that the dACC has strong functional connectivity with ipsilateral motor area and parietal gyrus. Repetitive Transcranial Magnetic Stimulation (rTMS) is a sage and painless technique to activate cortical areas. The deep brain structure can be activated via stimulating superficial cortex by rTMS. For investigating the mechanism of sustained attention, this project is using functional magnetic resonance imaging (fMRI) to individualize the precise localization in motor area and parietal gyrus, and combining rTMS to activate the dACC.
Healthy subject is recruiting in this project. High rTMS will be performed. The 10-Hz stimulation is delivered at 100% of the subject's resting motor threshold via 60 trains of 3-s 10-Hz rTMS (30 pulses with 27-s duration per train).
1,514 studies on the registry are indexed under Attention Deficit Disorder with Hyperactivity; 255 are open to participants now.
This study's enrollment of 32 is below the median of 72 across 1,207 interventional studies indexed under Attention Deficit Disorder with Hyperactivity.
Browse Attention Deficit Disorder with Hyperactivity studies →Hangzhou Normal University is the lead sponsor of 21 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Real rTMS targeting motor area for 30 min
Device: rTMS
Real rTMS targeting parietal gyrus for 30 min
Device: rTMS
Real rTMS targeting motor area and parietal gyrus for 15 min, separately
Device: rTMS
Sham rTMS targeting motor area and parietal gyrus for 15 min, separately
Device: rTMS
The 10-Hz stimulation is delivered at 100% of the subject's resting motor threshold via 60 trains of 3-s 10-Hz rTMS (30 pulses with 27-s duration per train).
degree of enhanced neuro-activity associated with target-specific treatment
amplitude of low frequency fluctuation
Time frame: through study completion, an average of 1 year
Plan to share: No — The IPD data cannot be shared with other researchers right now. We will shared it two years later.
This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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Attention Deficit Disorder with Hyperactivity→
Hangzhou Normal University