An interventional study of Platelet rich plasma clot implantation and Wound closure with amniotic membrane in Corneal Perforation, sponsored by Minia University. Completed at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2021-05-19.
Sponsored by Minia University · Not applicable, Interventional, and Treatment
Use of amniotic membrane(AMT) and platelet rich plasma (PRP) clot for closure of central corneal perforation
Use of amniotic membrane and platelet rich plasma clot for closure of central corneal perforation either post infective or posttraumatic
Minia University is the lead sponsor of 356 studies on the registry; 115 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients who had/impeding corneal perforation due to melting of the cornea after infection with a corneal pathogen (bacterial or viral), with no previous surgical intervention. Patients will undergo: Platelet rich plasma clot implantation Wound closure with amniotic membrane
Procedure: Platelet rich plasma clot implantation · Procedure: Wound closure with amniotic membrane
Implantation of a platelet rich plasma clot, which is created from the plasma of the patients, and refrigerated to be inserted under the sealing amniotic membrane
Closure of the corneal perforation with a synthetic amniotic membrane with a 2 mm safety margin
Closure of the corneal wound
sealing of the edges corneal gap, with formation of scar tissue
Time frame: 3 months
Plan to share: No — steps of technique and results
No publications or documents are linked to this record.
This study is completed, as verified in May 2021. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Corneal Perforation
Minia University