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CompletedNCT03499977ACEUpdated May 6, 2024

Acute Cycling on Executive Control

An interventional study of Sitting and Light-Intensity Cycling in Physical Activity, sponsored by Western University, Canada. Completed at 1 site in Canada. Open to participants aged 18 Years to 64 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-05-06.

Sponsored by Western University, Canada · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 64 Years
Sex
All
01

Study summary

This study will examine whether 10-minute bouts of cycling at various intensities will impact executive functioning (i.e., cognitive ability) as assessed by the antisaccade (AS) task through a total of five visits. An antisaccade is a rapid eye movement away from a visual target. The ability to suppress making an eye movement towards a visual target gauges inhibitory control (i.e., a domain of executive functioning). In the initial visit, participants' exercise capacity will be assessed through a maximal effort cycling test. Intensities for the cycling bouts (i.e., high, moderate, low) in subsequent sessions will be based upon this maximal effort cycling test. In visits 2 through 5, participants will complete an AS task, followed by a 10-minute bout of cycling, and then complete the AS task again. The order of cycling intensities will be randomized between participants. Differences in the AS task (i.e., reaction time and accuracy) will be compared between and within cycling conditions.

02

Conditions studied

  • Physical Activity

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Keywords

  • Physical Activity
  • Executive function
  • Anti-saccade
03

In context

Motor Activity

2,649 studies on the registry are indexed under Motor Activity; 1,205 are open to participants now.

This study's enrollment of 20 is below the median of 60 across 2,309 interventional studies indexed under Motor Activity.

Browse Motor Activity studies →

Lead sponsor

Western University, Canada is the lead sponsor of 224 studies on the registry; 56 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 64 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Able to read, write and understand English
  • Full time student enrolled at Western University
  • Able to perform a ten-minute exercise task at a light intensity without health implications
  • Have email or phone number for contacting purposes

Exclusion criteria

Exclusion Criteria:

  • Do not have a medical condition that prevents you from exercise (e.g. heart attack in the past year, heart disease, irregular heartbeat, etc.)
  • Do not have history of eye injury or neurological impairment
  • Do not have an orthopaedic limitation
  • Are not pregnant
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Sitting

    The participant will be asked to sit for 10 min (not increasing their heart rate) then do the anti-saccade task

    Behavioral: Sitting

  • Experimental
    Low-Intensity Cycling

    Participant will be asked to cycle for 10 min (\<40% VO2R) and then perform the anti-saccade task

    Behavioral: Light-Intensity Cycling

  • Experimental
    Moderate-Intensity Cycling

    The participant will be asked to do 10 min of cycling (40-59% VO2R) followed but the anti-saccade task

    Behavioral: Moderate-Intensity Cycling

  • Experimental
    High-Intensity Cycling

    The participant will be asked to do 10 min of cycling (60%-84% VO2R) followed but the anti-saccade task

    Behavioral: High-Intensity Cycling

Interventions

  • BehavioralSitting

    10 min bouts

  • BehavioralLight-Intensity Cycling

    10min bout

  • BehavioralModerate-Intensity Cycling

    10 min bout

  • BehavioralHigh-Intensity Cycling

    10 min bout

06

What researchers measure

Primary outcomes

  1. Reaction Time

    Time in milliseconds to target

    Time frame: 30 minutes

  2. Accuracy

    Directional errors

    Time frame: 30 minutes

Other outcomes

  1. Heart Rate

    Heart rate measured in beats per minute with a Polar Heart Rate Monitor as a manipulation check

    Time frame: 10 minutes

07

Study locations

1 site
  • Western University
    London, Ontario N6A3K7, Canada
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jul 2018 to primary completion in Dec 2018, 5 months.

Of 1,726 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 47. This study's 5 months is below that.

Counting every sponsor, half of 1,738 studies reached it within 23 months; a quarter within 9 and three quarters within 47.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 9, 2018
First posted
Apr 17, 2018
StartActual
Jul 1, 2018
Primary completionActual
Dec 31, 2018
CompletionActual
Jul 31, 2019
Last update
May 6, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 6, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03499977
Responsible party
Dr. Harry Prapavessis (Principal Investigator, Western University, Canada) — Principal investigator
First posted
Apr 17, 2018
Start date
Jul 1, 2018
Primary completion
Dec 31, 2018
Completion
Jul 31, 2019
Last update
May 6, 2024

Study contacts

Harry Prapavessis, Ph.D
principal investigator · Western University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.

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