An interventional study of Low dose Polyphenol and High dose Polyphenol in Skin Condition, sponsored by Access Business Group. Completed. Open to female participants aged 30 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-04-06.
Sponsored by Access Business Group · Not applicable, Interventional, and Prevention
The study is to assess skin attributes of female subjects following 16 weeks of dietary supplement consumption.
This is a 16 week, randomized, double blind, placebo controlled study. Approximately 105 Caucasian and Asian (Korean, Japanese, or Chinese) female subjects will be enrolled. The following clinical assessments will be performed: (1)VISIA-CR™ digital photography; (2)AGE Reader SU measurements on the left cheek and left inner forearm; (3) Visual Analog Grading (VAS); (4) Corneometer measurements; and (5) Cutometer measurements. Subjects will return to the clinic at approximately 4 weeks, 8 weeks and 16 weeks from the baseline visit for similar measurements. A self-perception questionnaire will be administered at the conclusion of the study.
496 studies on the registry are indexed under Skin Diseases; 77 are open to participants now.
This study's enrollment of 103 is above the median of 70 across 375 interventional studies indexed under Skin Diseases.
Browse Skin Diseases studies →Access Business Group is the lead sponsor of 11 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
130 mg of Aronia Extract with 120 mg of licorice root combination blend provided to subjects once per day for 16 weeks.
Dietary Supplement: Low dose Polyphenol
200 mg of Aronia extract provided to subjects once per day for 16 weeks
Dietary Supplement: High dose Polyphenol
Inert tablet provided to subjects once per day for 16 weeks
Dietary Supplement: Placebo Control
botanical supplement with 25 mg polyphenol
botanical supplement with 13 mg polyphenol
inert tablet made to mimic the experimental tablets
Change of Skin Autofluoresence
Change of accumulation of glycation as measured by validated autofluoresence measuring device (AGE Reader)
Time frame: Change from baseline to 16 weeks, change from 8 weeks to 16 weeks
Skin elasticity
Relationship between elasticity and skin glycation; elasticity will be measured by cutometer
Time frame: Change from baseline to 16 weeks; change from 8 weeks to 16 weeks
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Ran from Apr 2016 to primary completion in Jun 2017, 14 months.
Of 53 industry-sponsored interventional studies with no phase under Skin Diseases, half reached primary completion within 3 months of starting (the median), counting those still running; a quarter within 2 and three quarters within 9. This study's 14 months is above that.
Counting every sponsor, half of 95 studies reached it within 7 months; a quarter within 2 and three quarters within 22.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2018. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Polyphenol
Access Business Group