ClinicalTrials.gg
Active, not recruitingNCT03487224LOSSUpdated Aug 13, 2026

Neural Mechanisms of Decision Making in Hoarding Disorder

An observational study in Hoarding Disorder, sponsored by Stanford University. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-13.

Sponsored by Stanford University · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
25
Ages
18 Years to 70 Years
Sex
All
01

Study summary

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Read the detailed description

Hoarding disorder is a common and disabling disorder that represents a significant public health problem. This study aims to build on current research on decision making by examining these processes in hoarding disorder.

02

Conditions studied

  • Hoarding Disorder

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Keywords

  • Hoarding Disorder
03

In context

Hoarding Disorder

32 studies on the registry are indexed under Hoarding Disorder; 5 are open to participants now.

Browse Hoarding Disorder studies →

Lead sponsor

Stanford University is the lead sponsor of 2,168 studies on the registry; 431 are open to participants now.

Of its 267 completed or terminated interventional studies of FDA-regulated products, 207 (78%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Individuals with Hoarding Disorder and Healthy Participants

Eligibility criteria

Identify inclusion criteria.

Inclusion criteria for participants diagnosed with HD:

  1. ages 18-70
  2. primary diagnosis of hoarding disorder
  3. sufficient severity of hoarding symptoms
  4. stable on psychotropic medications for 1 month prior to study enrollment
  5. capacity to provide
  6. ability to tolerate clinical study procedures

Inclusion criteria for healthy control participants:

  1. ages 18-70
  2. capacity to provide informed consent

Identify exclusion criteria.

Exclusion criteria for participants with HD:

  1. psychiatric or medical conditions that make participation unsafe
  2. pregnant or nursing females
  3. concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)
  4. presence of metallic device or dental braces

Exclusion criteria for healthy control participants:

  1. any current or lifetime psychiatric diagnosis
  2. current or past use of psychotropic medication
  3. pregnant or nursing females
  4. major medical or neurological problem
  5. presence of metallic device or dental braces
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
25 participants (estimated)
Patient registry
No

Groups and cohorts

  • Hoarding Disorder

    Adults diagnosed with Hoarding Disorder

    Device: MRI with fMRI frequency

  • Healthy Controls

    Adults without mental illness

    Device: MRI with fMRI frequency

Interventions

  • DeviceMRI with fMRI frequency

    Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

06

What researchers measure

Primary outcomes

  1. BOLD signal

    BOLD signal derived from fMRI

    Time frame: up to 90 minutes

07

Study locations

1 site
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References and documents

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jul 2018 (actual). Primary completion is estimated for May 2027, 106 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 27, 2018
First posted
Apr 3, 2018
StartActual
Jul 8, 2018
Primary completionEst.
May 30, 2027
CompletionEst.
May 30, 2027
Last update
Aug 13, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03487224
Responsible party
Carolyn Rodriguez (Assistant Professor, Stanford University) — Principal investigator
First posted
Apr 3, 2018
Start date
Jul 8, 2018
Primary completion
May 30, 2027 (estimated)
Completion
May 30, 2027 (estimated)
Last update
Aug 13, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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