CClinicalTrials.gg
Status unknownNCT03486132Updated Apr 3, 2018

Repair of Lateral And Mediolateral Episiotomy

An interventional study of repair of episiotomy in Episiotomy Wound, sponsored by Ain Shams University. Status unknown at 1 site in Egypt. Open to female participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2018-04-03.

Sponsored by Ain Shams University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Mar 2018), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
240
Allocation
Randomized
Ages
20 Years to 40 Years
Sex
Female
01

Study summary

Episiotomy is an incision in the perineum carried out during the second stage of labour to facilitate the birth of an infant. It is an important surgical procedure with physiological, psychological and socio-economic effects on women. Therefore, not only the decision to carry out an episiotomy but also how it is performed and the quality of aftercare are important The two most often performed are the lateral and median episiotomy, as well as mediolateral episiotomy.

Two common methods of repair of episiotomy include continuous and interrupted methods This study aims to compare between postoperative pain following repair of episiotomy by continuous or interrupted suturing.

Read the detailed description

Aim of the work:

This study aims to compare between postoperative pain following repair of episiotomy by continuous or interrupted suturing.

Study population:

All primipara full term women with episiotomy done in a selective rather than liberal use.

E- Patients in the study will be randomized into one of two groups either those who have:

  1. Interrupted technique of episiotomy repair or
  2. Continuous knotless suturing technique and each of the two groups will be subdivided into either medio-lateral or lateral episiotomy.

The Episiotomy in group A will be done using the interrupted suture (IT) which involves placing three layers of sutures: a continuous non-locking stitch to close the vaginal epithelium. commencing above the apex of the wound and finishing at the level of the fourchette; three or four interrupted sutures to reapproximate the deep and superficial perineal muscles; and interrupted transcutaneous technique to close the skin.

The Episiotomy in group B will be done using the continuous knotless suturing technique (CKT) which involves placing the first stitch above the apex of vaginal trauma to secure any bleeding points that might not be visible. Vaginal wound, perineal muscles (deep and superficial), and skin are reapproximated with a loose, continuous, non-locking technique. The skin sutures will be placed closely fairly deeply in the subcutaneous tissue, reversing back and finishing with a terminal knot placed in the vagina beyond the hymeneal remnants.

And subgroups subjected to Mediolateral episiotomy:it is defined as an incision beginning in the midline and directed laterally and downwards away from the rectum .The incision is usually about four centimeters long. In addition to the skin and subcutaneous tissues the bulbocavernosus, transverse perineal, and puborectalis muscles will be cut. And Lateral episiotomy; It begins in the vaginal introitus 1 or 2 cm lateral to the midline and is directe downwards towards the ischial tuberosity.

The standard suture material in the study will be EGYSORB (sterile coated synthetic polyglycolic acid absorbable braided suture) No 2/0, Manufacturer TAISIER-MED Company).

F- Written informed consent will be taken from all women participating in our search.

G- Data recording: age,weight,height,body mass index,type of anesthesia used,type of episiotomy,time taken,infection or gaped episiotomy, amount of bleeding, postpartum hemorrhage,amount of suture material used,amount of analgesia used, severity of pain detected by VAS.

H- all patient will be given oral nonnarcotic analgesics (NSAIDs eg; ibuprofen 600 mg every eight hours for three days , if NSAIDs is contraindicated acetaminophen/ paracetamol 500 mg every eight hours for three days.

I- Antibiotic prophylaxis will be given as a single dose of a broad spectrum antibiotic (second generation cephalosporin or clindamycin if the patient is allergic to penicillin

02

Conditions studied

  • Episiotomy Wound
03

Who can participate

Ages eligible
20 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  1. Primipara women.
  2. Fullterm pregnancy.
  3. Lateral or mediolateral episiotomy done in selective rather than liberal episiotomy.

Exclusion criteria

Exclusion Criteria:

  1. Risk factor of trauma eg; macrosomia, congenital fetal malformations as (exophthalmous major, hydrocephalus, spinal cord teratoma....etc.
  2. Instrumental delivery.
  3. Primipara refuses to be in the study.
  4. Other techniques of episiotomy.
  5. Preterm onset of labour.
  6. Indication for CS eg; CPD, malposition and malpresentation, fetal distress....etc.
  7. Use of epidural analgesics.
  8. Factors affecting wound healing eg;DM, corticosteroid therapy, chronic debilitating diseases...etc.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
240 participants (estimated)

Study arms

  • Other
    interrupted repair of mediolateral episiotomy

    using the interrupted suture (IT) which involves placing three layers of sutures: a continuous non-locking stitch to close the vaginal epithelium. commencing above the apex of the wound and finishing at the level of the fourchette; three or four interrupted sutures to reapproximate the deep and superficial perineal muscles; and interrupted transcutaneous technique to close the skin. The standard suture material in the study will be EGYSORB (sterile coated synthetic polyglycolic acid absorbable braided suture) No 2/0 Mediolateral episiotomy:it is defined as an incision beginning in the midline and directed laterally and downwards away from the rectum .The incision is usually about four centimeters long. In addition to the skin and subcutaneous tissues the bulbocavernosus, transverse perineal, and puborectalis muscles will be cut

    Procedure: repair of episiotomy

  • Other
    continous repair of mediolateral episiotomy

    continuous knotless suturing technique (CKT) which involves placing the first stitch above the apex of vaginal trauma to secure any bleeding points that might not be visible. Vaginal wound, perineal muscles (deep and superficial), and skin are reapproximated with a loose, continuous, non-locking technique. The skin sutures will be placed closely fairly deeply in the subcutaneous tissue, reversing back and finishing with a terminal knot placed in the vagina beyond the hymeneal remnants Mediolateral episiotomy:it is defined as an incision beginning in the midline and directed laterally and downwards away from the rectum .The incision is usually about four centimeters long. In addition to the skin and subcutaneous tissues the bulbocavernosus, transverse perineal, and puborectalis muscles will be cut The standard suture material in the study will be EGYSORB (sterile coated synthetic polyglycolic acid absorbable braided suture) No 2/0

    Procedure: repair of episiotomy

  • Other
    interrupted repair of lateral episiotomy

    using the interrupted suture (IT) which involves placing three layers of sutures: a continuous non-locking stitch to close the vaginal epithelium. commencing above the apex of the wound and finishing at the level of the fourchette; three or four interrupted sutures to reapproximate the deep and superficial perineal muscles; and interrupted transcutaneous technique to close the skin. The standard suture material in the study will be EGYSORB (sterile coated synthetic polyglycolic acid absorbable braided suture) No 2/0 And Lateral episiotomy; It begins in the vaginal introitus 1 or 2 cm lateral to the midline and is directe downwards towards the ischial tuberosity

    Procedure: repair of episiotomy

  • Other
    continuous repair of lateral episiotomy

    continuous knotless suturing technique (CKT) which involves placing the first stitch above the apex of vaginal trauma to secure any bleeding points that might not be visible. Vaginal wound, perineal muscles (deep and superficial), and skin are reapproximated with a loose, continuous, non-locking technique. The skin sutures will be placed closely fairly deeply in the subcutaneous tissue, reversing back and finishing with a terminal knot placed in the vagina beyond the hymeneal remnants And Lateral episiotomy; It begins in the vaginal introitus 1 or 2 cm lateral to the midline and is directe downwards towards the ischial tuberosity The standard suture material in the study will be EGYSORB (sterile coated synthetic polyglycolic acid absorbable braided suture) No 2/0

    Procedure: repair of episiotomy

Interventions

  • Procedurerepair of episiotomy

    Different techniques for repair of episiotomy incsicion

05

What researchers measure

Primary outcomes

  1. postoperative pain

    using visual analogue scale

    Time frame: 6 hours

Secondary outcomes

  1. Postoperative pain two monthes after delivery.

    using VAS

    Time frame: TWO MONTHS

  2. Time taken in repair (min)

    Time frame: 1 hour

  3. Number of suture ampoules used.

    Time frame: 1 hour

  4. Dyspareunia

    Dyspareunia reported up to two months after delivery (ACOG;1995). according to Marinoff dyspareunia scale: 0 = no dyspareunia; 1. = causes discomfort, but does not interfere with the frequency of intercourse; 2. = sometimes prevents intercourse; and 3. = completely prevents intercourse.

    Time frame: two months

  5. Early complication of episiotomy eg; anal spincter injury, rectal mucosal injury, bleeding or heamatoma formation.

    Time frame: 1 hour

06

Study locations

1 of 1 sites recruiting
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03486132
Lead sponsor
Ain Shams University
Responsible party
mohammed mahmoud samy (Dr. Mohamed Samy, Ain Shams University) — Principal investigator
First posted
Apr 3, 2018
Start date
Jul 15, 2017
Primary completion
May 2018 (estimated)
Completion
May 2018 (estimated)
Last update
Apr 3, 2018

Study contacts

Mohamed Samy, MD
Contact
mohammedsamy8132@gmail.com
01001947488

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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