ClinicalTrials.gg
Active, not recruitingNCT03475147Updated Sep 8, 2026

Smartphone Flicker Fusion Test for Patients With Optic Disorders.

An interventional study of eyeFusion in Scotoma, sponsored by Randy Kardon. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-08.

Sponsored by Randy Kardon · Not applicable, Interventional, and Screening

From the registry’s dates

  • Registered 1 year 1 month after the study started (first participant enrolled Jan 2017, registered Mar 2018).
Phase
Not applicable
Study type
Interventional
Enrollment
500
Allocation
Non-randomized
Ages
18 Years to 80 Years
Sex
All
01

Study summary

The purpose of this project is to validate a quick, easy-to-use and administer smartphone flicker fusion test. The app (called eyeFusion) can potentially be used to easily and quickly collect critical flicker fusion measurements on patients admitted with optic disorders as part of the clinical care process.

Read the detailed description

The smartphone app developed is a flicker fusion that presents the subject with a series of stimuli consisting of a flickering pattern of bars above or below a static rectangle. For each stimulus presentation, the user has to tap the region that is flickering. The duration of the app is less than 2 minutes.

This study will assess the validity of the test construct in measuring flicker fusion thresholds, and serve as a foundation for further iterative designs of the app and future validation and characterization studies.

02

Conditions studied

  • Scotoma
03

In context

Lead sponsor

Randy Kardon is the lead sponsor of 4 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Inclusion Criteria:

Control

  • Age matched 18-80 years of age.
  • Healthy normal controls with no known eye disorders.

Exclusion Criteria:

  • Scotoma or any other ocular disorder

Inclusion Criteria - Patients

  • Age 18-80
  • Clinically associated scotoma

Exclusion Criteria - Patients

-Any other ocular disorder

05

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
500 participants (estimated)

Study arms

  • Active comparator
    eyeFusion Control Subjects

    Healthy normal controls with no known eye disorders age 18-80.

    Device: eyeFusion

  • Experimental
    eyeFusion Patients

    Scotoma subjects aged 18-80.

    Device: eyeFusion

Interventions

  • DeviceeyeFusion

    Smartphone app based flicker fusion test.

06

What researchers measure

Primary outcomes

  1. Assess Validity of the test construct measuring flicker fusion thresholds.

    The smartphone app developed is a flicker fusion that presents the subject with a series of stimuli consisting of a flickering pattern of bars above or below a static rectangle. The study will assess the validity of the test construct in measuring flicker fusion thresholds, and serve as a foundation for further iterative designs of the app and future validation and characterization studies.

    Time frame: 1/1/2020

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03475147
Lead sponsor
Randy Kardon
Responsible party
Randy Kardon (MD, PhD, University of Iowa) — Sponsor-investigator
First posted
Mar 23, 2018
Start date
Jan 27, 2017
Primary completion
Jan 1, 2028 (estimated)
Completion
Jan 1, 2028 (estimated)
Last update
Sep 8, 2026

Study contacts

Randy Kardon, MD, PhD
principal investigator · University of Iowa

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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