An interventional study of Optiflow with an inspired fraction of oxygen of 100% and Optiflow with an inspired fraction of oxygen of 21% in Dyspnea and Healthy Volunteers, sponsored by Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil. Completed at 2 sites in France. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-02-15.
Sponsored by Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil · Not applicable, Interventional, and Treatment
To develop an experimental model of dyspnea by external thoraco-abdominal elastic strapping at rest in order to study the mechanisms involved in the relief of dyspnea by the administration of high flow by nasal cannula (HFNC).
This study will measure the effect of HFNC on an experimental model of dyspnea induced by thoraco-abdominal elastic strapping on healthy subjects at rest.
The study will also compare the effects on dyspnea of the administration of high flow nasal cannula with and without oxygen added.
Exclusion Criteria:
Optiflow with an inspired fraction of oxygen of 100% in the first seance Optiflow with an inspired fraction of oxygen of 21 % in the second seance
Device: Optiflow with an inspired fraction of oxygen of 100% · Device: Optiflow with an inspired fraction of oxygen of 21%
Optiflow with an inspired fraction of oxygen of 21 % in the first seance Optiflow with an inspired fraction of oxygen of 100 % in the second seance
Device: Optiflow with an inspired fraction of oxygen of 100% · Device: Optiflow with an inspired fraction of oxygen of 21%
Respiratory gaz heated and humidified system of delivery with a fraction of oxygen inspired of 100%
Also known as: High flow nasal cannula with oxygen added
Respiratory gaz heated and humidified system of delivery with a fraction of oxygen inspired of 21%
Also known as: High flow nasal cannula without oxygen added
Effects of high flow nasal cannula on strapping induced type of dyspnea
Evaluated by visual annylogic scale
Time frame: One hour
Compare the effect of the high flow by nasal cannula with and without oxygen on an experimental dyspnea, evaluated by the differences of changes in the visual analogic scale
Evaluated by visual annylogic scale
Time frame: One hour
Plan to share: No
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This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.
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Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil